RABEP1 and GGA3

Number of citations of the paper that reports this interaction (PubMedID 12505986)
56

Data Source:
HPRD (two hybrid, in vivo)

		RABEP1	GGA3
Description		rabaptin, RAB GTPase binding effector protein 1	golgi associated, gamma adaptin ear containing, ARF binding protein 3
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GO Annotations	Cellular Component	Endosome Early Endosome Endocytic Vesicle Early Endosome Membrane Protein-containing Complex Intracellular Membrane-bounded Organelle Recycling Endosome	Lysosome Golgi Apparatus Trans-Golgi Network Endosome Membrane Early Endosome Membrane Protein-containing Complex Recycling Endosome Membrane
	Molecular Function	GTPase Activator Activity Protein Binding Growth Factor Activity Protein Domain Specific Binding Protein Homodimerization Activity	Protein Binding Small GTPase Binding Phosphatidylinositol Binding Ubiquitin Binding Protein-containing Complex Binding
	Biological Process	Golgi To Plasma Membrane Transport Endocytosis Apoptotic Process Signal Transduction Protein Transport Vesicle-mediated Transport Regulation Of Catalytic Activity Membrane Fusion Protein Localization To Ciliary Membrane	Protein Targeting To Lysosome Intracellular Protein Transport Regulation Of Protein Stability Protein Destabilization Endocytic Recycling Protein Localization To Cell Surface Golgi To Plasma Membrane Protein Transport Positive Regulation Of Protein Catabolic Process Negative Regulation Of Amyloid-beta Formation
Pathways		TBC/RABGAPs	TBC/RABGAPs MET receptor recycling Amyloid fiber formation
Drugs
Diseases
GWAS		Body mass index ( 28892062 25673413) Lymphocyte counts ( 32888494) Mean platelet volume ( 32888494) Red blood cell density in sickle cell anemia ( 28552477) White blood cell count ( 27863252)
Interacting Genes		59 interacting genes: ABI2 AIMP2 AP1G1 AP1G2 ATXN7 BARD1 CASP3 CCDC120 CCND1 CDC73 CDK18 CDKL3 CEP57 CFAP53 DDX3X ELOA ESCO2 FAM50B FAM90A1 GAP43 GGA1 GGA2 GGA3 HUNK ITSN1 LENG1 MAT2B MCRS1 ODAD3 PELI2 PKP2 PRPF3 RAB1A RAB33B RAB4A RAB4B RAB5A RABGEF1 RGS17 RNF39 SMURF1 SNAPIN SNW1 SRPK2 STAR TNS4 TRAPPC2L TRIM26 TSC2 TSHZ2 UBC UBTFL1 USP2 UTP14C WASHC3 YWHAG ZNF438 ZNF512B ZNF774	38 interacting genes: ADRA2A ADRA2B AFTPH AP1S2 ARAP3 ARF1 ARF3 CDKN2A CLINT1 CLTC CYTH2 DAZAP2 EGFR GGA1 GGA2 IGF2R LITAF LRP10 M6PR P4HA3 PACS1 PLEKHB2 RABEP1 RNF11 RNF214 RPS27A STAB1 SYNRG TBC1D3 TOLLIP TRAPPC6A TRIM23 TSG101 UBC UPRT VPS11 VPS18 ZNF497
Entrez ID		9135	23163
HPRD ID		04684	10443
Ensembl ID		ENSG00000029725	ENSG00000125447
Uniprot IDs		B4DMM4 Q15276	A8K6M0 B7Z456 Q9NZ52
PDB IDs		1P4U 1TU3 1X79 4N3Y 4N3Z 4Q9U	1JPL 1JUQ 1LF8 1P4U 1WR6 1YD8
Enriched GO Terms of Interacting Partners?
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