PRPF3 and NACC1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PRPF3	NACC1
Description		pre-mRNA processing factor 3	nucleus accumbens associated 1
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Cytosol Cajal Body Nuclear Speck U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome	Nucleus Nucleoplasm Cytoplasm Cell Junction Intracellular Membrane-bounded Organelle
	Molecular Function	RNA Binding Protein Binding Identical Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Histone Deacetylase Binding
	Biological Process	Spliceosomal Tri-snRNP Complex Assembly RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Cell Population Proliferation Negative Regulation Of Transcription, DNA-templated
Pathways		mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 33339817) Ambidextrousness ( 32989287) Blood protein levels ( 28240269) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Chronotype ( 27494321) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Hip index ( 34021172) Low density lipoprotein cholesterol levels ( 30498476) Morning person ( 30696823) Morning vs. evening chronotype ( 27494321) Platelet count ( 32888494 27863252) Plateletcrit ( 27863252) Refractive error ( 32231278) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) White blood cell count ( 32888494)	Obesity-related traits ( 23251661)
Interacting Genes		51 interacting genes: BRCA1 CARD10 CASK CCDC125 CCDC136 CCDC85B CDC5L CEP70 CTNNBL1 DPY30 DVL2 DVL3 FAM9B FCHO1 FRA10AC1 GOLGA2 GPRASP2 GTPBP3 HSF2BP LZTS1 MAPRE1 MID2 NACC1 NAV2 NINL NKAP NKAPD1 OSBPL3 PCBP1 PHC2 PIP4K2B PRPF31 PSMD3 RABEP1 RNF151 SART3 SHKBP1 SNIP1 SNRNP200 SSX2IP TRIM39 TSPYL1 TXLNA U2AF2 USP4 WBP4 ZBTB8A ZCCHC10 ZFPM2 ZGPAT ZRANB1	19 interacting genes: BCOR C8orf33 EHHADH ELOA HDAC3 HDAC4 LGALS8 LSM3 PML POLR2L PRKCI PRPF18 PRPF3 SENP1 SENP2 TARDBP UBE2I UBTFL1 ZNF512B
Entrez ID		9129	112939
HPRD ID		07389	10692
Ensembl ID		ENSG00000117360	ENSG00000160877
Uniprot IDs		O43395	A0A024R7E0 Q96RE7
PDB IDs		1X4Q 3JCR 5O9Z 6AH0 6AHD 6QW6 6QX9	3GA1 4U2N 7BV9
Enriched GO Terms of Interacting Partners?
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