SLC25A46 and SLC7A8

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SLC25A46	SLC7A8
Description		solute carrier family 25 member 46	solute carrier family 7 member 8
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Integral Component Of Membrane	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Basal Plasma Membrane Basolateral Plasma Membrane Apical Plasma Membrane Microvillus Membrane
	Molecular Function	Protein Binding	Protein Binding Organic Cation Transmembrane Transporter Activity Amino Acid Transmembrane Transporter Activity Neutral Amino Acid Transmembrane Transporter Activity L-amino Acid Transmembrane Transporter Activity L-alanine Transmembrane Transporter Activity Glycine Transmembrane Transporter Activity L-leucine Transmembrane Transporter Activity Thyroid Hormone Transmembrane Transporter Activity Toxin Transmembrane Transporter Activity Peptide Antigen Binding
	Biological Process	Mitochondrial Fission Axon Development Mitochondrial Membrane Fission	Amino Acid Transmembrane Transport Amino Acid Transport Response To Toxic Substance Organic Cation Transport Neutral Amino Acid Transport Glycine Transport Leucine Transport Tryptophan Transport Valine Transport Proline Transmembrane Transport Metal Ion Homeostasis Thyroid Hormone Transport Amino Acid Import Across Plasma Membrane Leucine Import Across Plasma Membrane Transport Across Blood-brain Barrier Toxin Transport L-leucine Import Across Plasma Membrane L-alanine Import Across Plasma Membrane
Pathways			Basigin interactions Amino acid transport across the plasma membrane
Drugs			Phenylalanine Alanine
Diseases
GWAS		Allergic disease (asthma, hay fever and/or eczema) (age of onset) ( 32603359) Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) ( 32603359) Allergic disease (asthma, hay fever or eczema) ( 29083406 29785011) Allergic sensitization ( 23817571) Asthma ( 31959851 30929738 34103634 27182965 31619474 29273806) Asthma (adult onset) ( 31036433 30929738) Asthma (age of onset) ( 31036433) Asthma (childhood onset) ( 31036433 30929738) Asthma and hay fever ( 24388013) Asthma onset (childhood vs adult) ( 30929738) Asthma or allergic disease (pleiotropy) ( 29785011) Cardiac structure and function ( 19584346) Medication use (adrenergics, inhalants) ( 31015401) Medication use (antihistamines for systemic use) ( 31015401) Thrombin-activatable fibrinolysis inhibitor levels ( 29378355) Uterine fibroid size (maximum volume) ( 30196971)
Interacting Genes		16 interacting genes: AQP6 FHL3 FUNDC1 HSD17B11 HSD17B13 LEPROTL1 MFSD14B ODF4 REEP2 REEP4 SLC10A1 SLC10A6 SLC66A2 SLC7A8 SPCS1 VMA21	26 interacting genes: ABHD16A AGPAT4 AQP6 COMT DERL1 FXYD6-FXYD2 MFF MFSD3 NDUFA3 NINJ2 REEP4 SIGLEC5 SLC25A46 SLC30A2 SLC3A1 SLC3A2 SMPD2 SNORC SYCE1L SYNJ2BP TMEM14B TMEM208 TMEM60 TMEM65 YIPF1 YIPF6
Entrez ID		91137	23428
HPRD ID		14283	11971
Ensembl ID		ENSG00000164209	ENSG00000092068
Uniprot IDs		B4DY98 Q96AG3	Q53EM9 Q9UHI5
PDB IDs			7CMH 7CMI
Enriched GO Terms of Interacting Partners?
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