SART1 and SRSF4

Number of citations of the paper that reports this interaction (PubMedID 22365833)
163

Data Source:
BioGRID (two hybrid, two hybrid)

		SART1	SRSF4
Description		spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP	serine and arginine rich splicing factor 4
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Cajal Body Nuclear Speck U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome Catalytic Step 2 Spliceosome	Nucleus Nucleoplasm Nuclear Speck
	Molecular Function	RNA Binding Protein Binding	RNA Binding MRNA Binding Protein Binding Sequence-specific MRNA Binding
	Biological Process	Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome Maturation Of 5S RRNA MRNA Cis Splicing, Via Spliceosome Positive Regulation Of Cytotoxic T Cell Differentiation	RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Response To Insulin Negative Regulation Of MRNA Splicing, Via Spliceosome
Pathways		mRNA Splicing - Major Pathway	Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs			Artenimol
Diseases
GWAS		Acne (severe) ( 24927181) Bipolar disorder ( 31043756) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634)	Carotid plaque maximum area ( 32469969) Hematocrit ( 32888494) Hemoglobin ( 32888494) Mean area of carotid plaque ( 32469969) Schizophrenia ( 26531332) Tourette syndrome ( 30818990)
Interacting Genes		13 interacting genes: APP CHERP HSF2BP IGHE PLAT SNW1 SRPK2 SRSF4 SUMO2 UBE2I UBL5 WBP4 ZCCHC10	23 interacting genes: DYRK1A FUS GEMIN2 HAP1 HTATSF1 PNN PPARGC1A PRPF38A RNPS1 SART1 SCAF11 SMURF1 SMURF2 SREK1 SRPK1 SRRM2 SRSF10 SRSF2 SRSF6 TICAM1 TRA2B UBE2I ZDHHC17
Entrez ID		9092	6429
HPRD ID		10440	09052
Ensembl ID		ENSG00000175467	ENSG00000116350
Uniprot IDs		O43290	Q08170
PDB IDs		4PYU 5O9Z 6AHD 6QW6 6QX9
Enriched GO Terms of Interacting Partners?
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