SEC11C and TSNARE1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SEC11C	TSNARE1
Description		SEC11 homolog C, signal peptidase complex subunit	t-SNARE domain containing 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Signal Peptidase Complex Endoplasmic Reticulum Membrane Integral Component Of Membrane	Endomembrane System Integral Component Of Membrane SNARE Complex
	Molecular Function	Serine-type Endopeptidase Activity Protein Binding Peptidase Activity	SNARE Binding SNAP Receptor Activity
	Biological Process	Signal Peptide Processing	Intracellular Protein Transport Vesicle Fusion Vesicle Docking
Pathways		SRP-dependent cotranslational protein targeting to membrane Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) Synthesis, secretion, and deacylation of Ghrelin
Drugs
Diseases
GWAS		Alzheimer's disease (age of onset) ( 22005931) Chronotype ( 30696823) Morning person ( 30696823)	Adult body size ( 32376654) Adventurousness ( 30643258) Age at first sexual intercourse ( 34211149) Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Anxiety ( 33859377) Anxiety/tension (special factor of neuroticism) ( 30867560) Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder x sex interaction ( 34099189) Body size at age 10 ( 32376654) Broad depression or schizophrenia ( 30626913) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Cognitive decline rate in late mild cognitive impairment ( 26252872) Feeling nervous ( 29500382) Feeling tense ( 29500382) General cognitive ability ( 29844566) General risk tolerance (MTAG) ( 30643258) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Intelligence (MTAG) ( 29326435) Mental health study participation (completed survey) ( 31263887) Monoclonal gammopathy of undetermined significance ( 30737484) Schizophrenia ( 28991256 25056061 29483656 30285260 23974872) Systolic blood pressure ( 30224653 30578418)
Interacting Genes		23 interacting genes: BTN2A2 C2 CADM3 GLP1R HMOX1 MFF PLPP6 PRSS23 RTP2 SCD SELENOM SERP1 STX12 TMEM128 TMEM243 TMEM254 TMEM42 TREX1 TSNARE1 UBE2J1 VAMP1 VAMP4 VAPA	29 interacting genes: CD79A CNIH4 CYB561 DYNLL1 EBP ELOVL4 ELOVL5 GPR152 JAGN1 LEPROTL1 LMNA MFSD14B REEP4 RETREG3 SEC11C SLC10A6 SLC35C2 SNAP29 STX1A TM4SF19 TMEM229B TMEM51 TMEM86B TMX2 TOP1MT VEZT YIPF4 ZDHHC15 ZNF707
Entrez ID		90701	203062
HPRD ID		15310	08708
Ensembl ID		ENSG00000166562	ENSG00000171045
Uniprot IDs		K7EJQ7 Q9BY50	E5RHT3 Q6P186 Q96NA8
PDB IDs
Enriched GO Terms of Interacting Partners?
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