CCRL2 and C4orf3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CCRL2	C4orf3
Description		C-C motif chemokine receptor like 2	chromosome 4 open reading frame 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane	Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Chemokine Receptor Activity C-C Chemokine Receptor Activity C-C Chemokine Binding Chemokine Receptor Binding CCR Chemokine Receptor Binding
	Biological Process	Chemotaxis Inflammatory Response Immune Response G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Calcium-mediated Signaling Cell Chemotaxis Chemokine-mediated Signaling Pathway	Negative Regulation Of Calcium Ion Binding Negative Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity
Pathways		Chemokine receptors bind chemokines
Drugs
Diseases
GWAS		AIDS progression ( 21502085) Blood protein levels ( 28240269) Celiac disease ( 20190752) Cerebrospinal fluid levels of Alzheimer's disease-related proteins ( 25340798) Lymphocyte percentage of white cells ( 32888494) Macular thickness ( 30535121) Monocyte percentage of white cells ( 27863252) Pre-treatment viral load in HIV-1 infection ( 31219150) Setpoint viral load in HIV-1 infection ( 26553974) Ulcerative colitis ( 28067908)	Blood protein levels ( 28240269)
Interacting Genes		2 interacting genes: C4orf3 PBRM1	67 interacting genes: ADGRG3 AQP2 AQP6 ARL13B BCL2L13 BIK C5AR2 CALM1 CCRL2 CD79A CISD2 CLDN9 CREB3L1 CXCR2 CYBC1 DEGS1 EBP ERGIC3 FAM174A FAM209A FFAR2 GJA5 GJB4 GJB5 GLP1R GPR61 HHATL HTR2C JAGN1 LAPTM5 LMNA LY6G6C MFSD14B MILR1 MMD MMGT1 MRM3 MS4A3 NCAPH2 PLEKHO1 PTGES REEP4 RETREG3 RHBDL1 RHCG SERINC2 SHISAL1 SLC14A2 SLC19A3 SLC35C2 SLC35E3 SLC39A2 SLC41A3 SLCO3A1 SMO SSMEM1 STX1A SYNPR TIMMDC1 TM4SF19 TMEM101 TMEM237 TMEM248 TMEM45A TMEM45B TMEM51 YIF1A
Entrez ID		9034	401152
HPRD ID		16327	14223
Ensembl ID		ENSG00000121797	ENSG00000164096
Uniprot IDs		B2R8C0 O00421	Q8WVX3
PDB IDs
Enriched GO Terms of Interacting Partners?
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