CLIC3 and MAPK15

Number of citations of the paper that reports this interaction (PubMedID 9880541)
32

Data Source:
HPRD (in vivo)

		CLIC3	MAPK15
Description		chloride intracellular channel 3	mitogen-activated protein kinase 15
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Membrane Nuclear Body Chloride Channel Complex Extracellular Exosome	Extracellular Region Nucleus Cytoplasm Autophagosome Golgi Apparatus Centriole Cell-cell Junction Bicellular Tight Junction Axoneme Cytoplasmic Vesicle Ciliary Basal Body Meiotic Spindle
	Molecular Function	Voltage-gated Ion Channel Activity Chloride Channel Activity Protein Binding	Chromatin Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity MAP Kinase Activity Protein Binding ATP Binding Kinase Activity SH3 Domain Binding Protein Serine Kinase Activity
	Biological Process	Glutathione Metabolic Process Chloride Transport Signal Transduction Ion Transmembrane Transport Regulation Of Ion Transmembrane Transport	MAPK Cascade Regulation Of COPII Vesicle Coating Cellular Response To DNA Damage Stimulus Endoplasmic Reticulum Organization Positive Regulation Of Cell Population Proliferation Regulation Of Autophagy Negative Regulation Of Cell Migration Positive Regulation Of Telomere Maintenance Via Telomerase Intracellular Signal Transduction Protein Autophosphorylation Positive Regulation Of Telomerase Activity Dopamine Uptake Regulation Of Cilium Assembly Positive Regulation Of Telomere Capping Protein Localization To Ciliary Transition Zone Positive Regulation Of Metaphase/anaphase Transition Of Meiosis I Positive Regulation Of Spindle Assembly
Pathways
Drugs			Acetylsalicylic acid Minocycline Fostamatinib
Diseases
GWAS			Obesity-related traits ( 23251661)
Interacting Genes		35 interacting genes: AGR2 ALX1 ANKRD23 ANKRD55 APP C7orf31 C9orf24 DDIT4L DNM1 EFHC2 FAM166B GLYR1 INCA1 KATNBL1 KRT85 KRTAP13-3 LELP1 MAPK15 MBD3L1 MECOM MIA3 MSX2 POT1 PROSER2 SCML4 STMN3 TBC1D3 TBC1D3C TBC1D3K TEPSIN TLE5 VPS4A ZBTB42 ZC2HC1C ZNF620	9 interacting genes: CLIC3 CSK GABARAP GABARAPL1 MBP NR3C1 RHEB SRC TGFB1I1
Entrez ID		9022	225689
HPRD ID		05941	16867
Ensembl ID		ENSG00000169583	ENSG00000181085
Uniprot IDs		O95833 Q6FGP1	Q8TD08
PDB IDs		3FY7 3KJY
Enriched GO Terms of Interacting Partners?
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