SOCS3 and CAVIN1

Number of citations of the paper that reports this interaction (PubMedID 32548823)
0

Data Source:
BioGRID (unspecified method)

		SOCS3	CAVIN1
Description		suppressor of cytokine signaling 3	caveolae associated protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Phosphatidylinositol 3-kinase Complex	Nucleus Nucleoplasm Cytoplasm Mitochondrion Endoplasmic Reticulum Cytosol Plasma Membrane Caveola Protein-containing Complex Intracellular Membrane-bounded Organelle Membrane Raft
	Molecular Function	Phosphotyrosine Residue Binding Protein Kinase Inhibitor Activity Protein Binding 1-phosphatidylinositol-3-kinase Regulator Activity	RNA Binding Protein Binding RRNA Primary Transcript Binding Identical Protein Binding
	Biological Process	Receptor Signaling Pathway Via JAK-STAT Protein Ubiquitination Intracellular Signal Transduction Regulation Of Growth Negative Regulation Of Tyrosine Phosphorylation Of STAT Protein Negative Regulation Of Apoptotic Process Negative Regulation Of Catalytic Activity Regulation Of Phosphatidylinositol 3-kinase Activity Positive Regulation Of Cell Differentiation Negative Regulation Of Receptor Signaling Pathway Via JAK-STAT Negative Regulation Of Insulin Receptor Signaling Pathway Phosphatidylinositol Phosphate Biosynthetic Process Negative Regulation Of Inflammatory Response Branching Involved In Labyrinthine Layer Morphogenesis Placenta Blood Vessel Development Trophoblast Giant Cell Differentiation Cellular Response To Leukemia Inhibitory Factor	Transcription Initiation From RNA Polymerase I Promoter Termination Of RNA Polymerase I Transcription RRNA Transcription Protein Secretion Positive Regulation Of Cell Motility
Pathways		Interleukin-6 signaling Signaling by Leptin Interleukin-4 and Interleukin-13 signaling Interferon gamma signaling Regulation of IFNG signaling PTK6 Activates STAT3 RUNX1 regulates transcription of genes involved in differentiation of keratinocytes Neddylation Interferon alpha/beta signaling Regulation of IFNA signaling Signaling by CSF3 (G-CSF) Inactivation of CSF3 (G-CSF) signaling Inactivation of CSF3 (G-CSF) signaling Growth hormone receptor signaling Antigen processing: Ubiquitination & Proteasome degradation	RNA Polymerase I Transcription Termination RHOA GTPase cycle RHOB GTPase cycle RHOC GTPase cycle
Drugs
Diseases
GWAS		Asthma ( 32296059) Blood trace element (Se levels) ( 23720494) Creatine kinase levels ( 29403010)
Interacting Genes		64 interacting genes: ABL1 ACADVL APP AR BCL10 BIK BLK CAVIN1 CSF1R CSF3R CSNK1E CUEDC2 CXCR4 EGFR ELOB ELOC EPOR ERBB2 ERBB3 ERBB4 GAB1 GFRA1 GHR HIVEP1 IGF1R IL12RB2 IL2RB IL6ST INSR IRF7 IRS1 IRS2 JAK1 JAK2 JAK3 KIAA1958 KIT LEPR MAP1S MAPK11 MAPK6 MET NME4 PDPK1 PIN1 PPP3CB PRLR PTK2 PTPN11 RASA1 RBMX RNF31 RNF7 RPL7A SH2D2A SOCS2 TES TFDP1 TFR2 TRDN TXK TXNDC11 YES1 YWHAQ	25 interacting genes: CAVIN3 CDC37 CDCA7L DNTTIP2 DUX4 ERCC6 FBXO28 INO80B KAT5 MRPL45 NKX2-1 OGT SOCS3 SPANXN2 SPANXN3 TNFAIP8L1 TSGA10IP TTC5 TTF1 UBC YAF2 ZCCHC10 ZFP1 ZNF148 ZSCAN21
Entrez ID		9021	284119
HPRD ID		05006	04433
Ensembl ID		ENSG00000184557	ENSG00000177469
Uniprot IDs		O14543 Q6FI39	Q6NZI2
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?