ACVR1 and FGD6

  • Number of citations of the paper that reports this interaction (PubMedID 15761153)
  • 269
  • Data Source:
  • HPRD (in vivo)

ACVR1

FGD6

Description activin A receptor type 1 FYVE, RhoGEF and PH domain containing 6
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Body shape index ( 34021172)
  • Severe gingival inflammation ( 28459102)
  • Waist circumference adjusted for body mass index ( 34021172)
  • Waist-hip index ( 34021172)
  • Waist-to-hip ratio adjusted for BMI ( 34021172)
  • Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin) ( 23648065)
  • Aging traits (healthspan, parental lifespan or longevity) (multivariate analysis) ( 32678081)
  • Brain morphology (MOSTest) ( 32665545)
  • Chronic obstructive pulmonary disease ( 30804561)
  • Coronary artery disease ( 29212778 33020668)
  • Exudative age-related macular degeneration ( 25629512)
  • Hip circumference ( 28552196)
  • Intracranial aneurysm ( 33199917)
  • Lung function (FEV1/FVC) ( 28166213 30804560)
  • Platelet count ( 32888494)
  • Platelet distribution width ( 32888494)
  • Pulse pressure ( 30224653)
  • White matter hyperintensity volume ( 33293549)
  • White matter hyperintensity volume (adjusted for hypertension) ( 33293549)
Interacting Genes 70 interacting genes: AP2B1 BAMBI BMP2 BMP6 BMP7 BMPR1A BMPR2 CDK14 CHN1 CREBBP DCAF6 DUSP13 ENG FANCL FBXO30 FBXO7 FCHO1 FGD6 FKBP4 FNTA GDF2 GDF5 IGSF1 IKBKB INHBA INHBB INHBC KLHL35 NEK8 NKIRAS1 NRAS NUAK2 OTUB1 PAK1 PLEK PLEKHB1 PLEKHJ1 RAB17 RAB25 RAB33B RAB3B RAB6B RAP2A RASD2 RASL12 RHEBL1 RHOD RHOJ RPS27A RRAS2 RXRA SMAD1 SMAD5 SMAD9 SOCS6 STIP1 STX8 TDGF1 TGFBR1 TGFBR2 THRB TTC17 TTC27 UBA52 UBE2E3 UBXN1 USP39 VDR VEPH1 WDR61 2 interacting genes: ACVR1 YWHAG
Entrez ID 90 55785
HPRD ID 00021 16892
Ensembl ID ENSG00000115170 ENSG00000180263
Uniprot IDs D3DPA4 Q04771 Q6ZV73
PDB IDs 3H9R 3MTF 3OOM 3Q4U 4BGG 4C02 4DYM 5OXG 5OY6 6ACR 6EIX 6GI6 6GIN 6GIP 6I1S 6JUX 6SRH 6SZM 6T6D 6T8N 6TN8 6Z36 6ZGC 7A21 7C3G
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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