SIGLEC12 and MGST1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SIGLEC12	MGST1
Description		sialic acid binding Ig like lectin 12	microsomal glutathione S-transferase 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Nucleus Mitochondrion Mitochondrial Outer Membrane Peroxisomal Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Membrane Azurophil Granule Membrane Apical Part Of Cell
	Molecular Function	Protein Binding Carbohydrate Binding Sialic Acid Binding	Glutathione Transferase Activity Glutathione Peroxidase Activity Protein Binding Identical Protein Binding Glutathione Binding
	Biological Process	Cell Adhesion	Response To Xenobiotic Stimulus Response To Organonitrogen Compound Response To Lipopolysaccharide Leydig Cell Differentiation Glutathione Transport Cellular Response To Lipid Hydroperoxide Cellular Oxidant Detoxification
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	Glutathione conjugation Aflatoxin activation and detoxification Neutrophil degranulation
Drugs			Glutathione Glutathione disulfide
Diseases
GWAS		Blood protein levels ( 29875488)	Barrett's esophagus or Esophageal adenocarcinoma ( 32918910) Barrett's esophagus or esophageal adenocarcinoma x sex interaction (2df test) ( 32918910) Bell's palsy ( 33602968) Colorectal cancer (aspirin and/or NSAID use interaction) ( 25781442) Household income (MTAG) ( 31844048) Metabolite levels ( 23823483) Metastatic colorectal cancer survival in treatment with chemotherapy plus biologics ( 32958699) Visceral fat ( 22589738)
Interacting Genes		18 interacting genes: ACSF2 ADIPOQ ATP5PF CDIPT CLEC4G CMAS CTSA DNAAF3 DNAJC30 IL1RL1 MGST1 PLPP6 PLPPR2 PTCH1 PTPN11 PTPN6 TMPRSS4 YIPF1	8 interacting genes: EGF FXYD3 FZD7 LTC4S NELFB SIGLEC12 TNFRSF10C VIP
Entrez ID		89858	4257
HPRD ID		16195	00705
Ensembl ID		ENSG00000254521	ENSG00000008394
Uniprot IDs		Q96PQ1	A0A024RAX2 P10620
PDB IDs
Enriched GO Terms of Interacting Partners?
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