KYNU and RASSF3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		KYNU	RASSF3
Description		kynureninase	Ras association domain family member 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Mitochondrion Cytosol	Cytoplasm Cytosol Microtubule Plasma Membrane
	Molecular Function	Pyridoxal Phosphate Binding Kynureninase Activity Protein Homodimerization Activity 3-hydroxykynureninase Activity	Protein Binding Identical Protein Binding
	Biological Process	Tryptophan Catabolic Process Aging NAD Biosynthetic Process Tryptophan Catabolic Process To Kynurenine Tryptophan Catabolic Process To Acetyl-CoA Quinolinate Biosynthetic Process Response To Interferon-gamma 'de Novo' NAD Biosynthetic Process From Tryptophan Response To Vitamin B6 Anthranilate Metabolic Process L-kynurenine Catabolic Process	Signal Transduction Regulation Of Apoptotic Process
Pathways		Tryptophan catabolism
Drugs		Pyridoxal phosphate Alanine m-Hydroxyhippuric acid
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406) Asthma ( 32296059) Blood protein levels ( 30072576 29875488 28240269) Cataracts ( 34127677) Empathy quotient ( 29527006) Glomerular filtration rate in chronic kidney disease ( 26420894) Neurological blood protein biomarker levels ( 31320639) Platelet count ( 32888494) Response to SSRI (symptom remission) ( 29160301) Toenail selenium levels ( 25343990)	Cardiometabolic and hematological traits ( 27668658) Lung adenocarcinoma ( 28604730) Lung function (FEV1/FVC) ( 30804560) Mean platelet volume ( 32888494 27863252) Platelet count ( 32888494 27863252) Prostate cancer ( 29892016) Resting heart rate ( 29769521 27798624)
Interacting Genes		9 interacting genes: CDC42 CT55 CTBP2 FAM86C1P LMO4 MCCD1 MYOZ3 PIP4K2B RASSF3	14 interacting genes: APP CBX8 DAXX FAM110A ITPRIP KDM1A KYNU LITAF PARD6B RPRD1B TENT5D TFRC TRIM59 ZNF410
Entrez ID		8942	283349
HPRD ID		08940	08448
Ensembl ID		ENSG00000115919	ENSG00000153179
Uniprot IDs		Q16719	Q86WH2
PDB IDs		2HZP 3E9K
Enriched GO Terms of Interacting Partners?
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