HERC1 and PKM

  • Number of citations of the paper that reports this interaction (PubMedID 12650930)
  • 10
  • Data Source:
  • HPRD (in vivo, two hybrid, in vitro)

HERC1

PKM

Description HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 pyruvate kinase M1/2
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Apolipoprotein A1 levels ( 32203549)
  • Atrial fibrillation ( 30061737)
  • Body shape index ( 34021172)
  • Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143)
  • Disease progression in age-related macular degeneration (adjusted for baseline) ( 29346644)
  • Glucagon levels in response to oral glucose tolerance test (120 minutes) ( 29093273)
  • Iris characteristics ( 21835309)
  • Reticulocyte fraction of red cells ( 27863252)
  • Waist circumference adjusted for body mass index ( 34021172)
  • Waist-hip index ( 34021172)
  • Waist-to-hip ratio adjusted for BMI ( 34021172)
  • Aspartate aminotransferase levels ( 33547301)
Interacting Genes 12 interacting genes: BAK1 EP300 LAPTM5 PKM RAF1 RNF11 SOX9 UBC UBE2D2 UBE2D3 UBE2L3 UBE2S 63 interacting genes: ANXA7 APP ARAF ARX AURKB CCR4 CDC25A CDK4 CDKN1A CTNNB1 DLC1 DUX4 EGLN3 ENO3 EPM2A EXOSC5 FGFR1 FXR1 FXR2 GRB7 HERC1 HIF1A HOXA1 HSP90AA1 HULC KPNA1 LINC01554 LMO7 LNX1 MAPK1 MDM2 MYL2 MYOC NAGK NDRG1 NXT2 OGT OLFM2 PAX8 PIN1 POLE2 PRKN PTEN RAF1 RAP1B RCC1 RELA RPP14 SHBG SMN1 SORBS2 SUMO1 SUMO2 TERF1 TINF2 TK1 TRIM35 TRIM55 TRIM63 UBE3A UCHL5 USP7 YWHAQ
Entrez ID 8925 5315
HPRD ID 06894 01529
Ensembl ID ENSG00000103657 ENSG00000067225
Uniprot IDs A0A024R5W0 Q15751 A0A024R5Z9 B4DNK4 P14618 V9HWB8
PDB IDs 4O2W 4QT6 1T5A 1ZJH 3BJF 3BJT 3G2G 3GQY 3GR4 3H6O 3ME3 3SRD 3SRF 3SRH 3U2Z 4B2D 4FXF 4FXJ 4G1N 4JPG 4QG6 4QG8 4QG9 4QGC 4RPP 4WJ8 4YJ5 5X0I 5X1V 5X1W 6B6U 6GG3 6GG4 6GG5 6GG6 6JFB 6NU1 6NU5 6NUB 6TTF 6TTH 6TTI 6TTQ 6V74 6V75 6V76 6WP3 6WP4 6WP5 6WP6
Enriched GO Terms of Interacting Partners?
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