BUD31 and NPC1

Number of citations of the paper that reports this interaction (PubMedID 28298427)
23

Data Source:
BioGRID (two hybrid)

		BUD31	NPC1
Description		BUD31 homolog	NPC intracellular cholesterol transporter 1
Image
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Spliceosomal Complex U2-type Catalytic Step 2 Spliceosome	Extracellular Region Nuclear Envelope Lysosome Lysosomal Membrane Endoplasmic Reticulum Golgi Apparatus Integral Component Of Plasma Membrane Membrane Integral Component Of Membrane Late Endosome Membrane Membrane Raft Perinuclear Region Of Cytoplasm Extracellular Exosome Integral Component Of Lysosomal Membrane
	Molecular Function	Protein Binding Nuclear Receptor Binding Nuclear Receptor Coactivator Activity	Virus Receptor Activity Transmembrane Signaling Receptor Activity Protein Binding Sterol Transporter Activity Cholesterol Binding Signaling Receptor Activity
	Biological Process	MRNA Splicing, Via Spliceosome Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Androgen Receptor Activity	Protein Glycosylation Endocytosis Autophagy Lysosomal Transport Adult Walking Behavior Cholesterol Metabolic Process Bile Acid Metabolic Process Response To Xenobiotic Stimulus Gene Expression Negative Regulation Of Macroautophagy Cholesterol Transport Membrane Raft Organization Intracellular Cholesterol Transport Cholesterol Efflux Cholesterol Homeostasis Response To Cadmium Ion Viral Entry Into Host Cell Negative Regulation Of Cell Death Cellular Response To Steroid Hormone Stimulus Cellular Response To Low-density Lipoprotein Particle Stimulus Establishment Of Protein Localization To Membrane
Pathways		mRNA Splicing - Major Pathway	LDL clearance
Drugs
Diseases
GWAS		Facial emotion recognition (sad faces) ( 28608620) Serum metabolite levels ( 23093944)	Adult body size ( 32376654) Apolipoprotein A1 levels ( 32203549) Body mass index ( 29273807) Body size at age 10 ( 32376654) Chronotype ( 30696823) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Coronary artery disease ( 29212778) Granulocyte count ( 27863252) HDL cholesterol ( 30275531) HDL cholesterol levels ( 32203549) Household income (MTAG) ( 31844048) Mental health study participation (provided email address) ( 31263887) Metabolic syndrome ( 31589552) Monocyte percentage of white cells ( 32888494) Myeloid white cell count ( 27863252) Neutrophil count ( 27863252) Obesity ( 19151714) Poultry consumption ( 32066663) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) Triglyceride levels ( 32203549 32154731) Triglycerides ( 30275531) Walking pace ( 33128006) White blood cell count ( 27863252)
Interacting Genes		23 interacting genes: ADCY7 APP ATP13A1 BEND5 CCT3 CTNNBL1 ERGIC3 HLA-A HOXA1 HTR5A KRTAP10-3 KRTAP10-7 MARCHF6 MEOX2 MMP24 NPC1 PANX1 PICK1 RELB RNF208 SCAF1 TMEM94 TSPAN7	6 interacting genes: BUD31 FURIN GPR35 MC4R MTDH VPS4A
Entrez ID		8896	4864
HPRD ID		10351	09622
Ensembl ID		ENSG00000106245	ENSG00000141458
Uniprot IDs		P41223	O15118
PDB IDs		4OED 4OH6 4OKB 5MQF 5XJC 5YZG 5Z56 5Z57 6FF4 6FF7 6ICZ 6ID0 6ID1 6QDV 6ZYM 7AAV 7ABF 7ABG 7ABI	3GKH 3GKI 3GKJ 3JD8 5F18 5F1B 5HNS 5JNX 5KWY 5U73 5U74 6UOX 6W5R 6W5S 6W5T 6W5U 6W5V
Enriched GO Terms of Interacting Partners?
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