IQGAP1 and PKNOX2

  • Number of citations of the paper that reports this interaction (PubMedID 32296183)
  • 86
  • Data Source:
  • BioGRID (two hybrid)

IQGAP1

PKNOX2

Description IQ motif containing GTPase activating protein 1 PBX/knotted 1 homeobox 2
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alcohol and nicotine co-dependence ( 22488850)
  • Alcohol dependence ( 21956439 21703634)
  • Alcohol dependence symptom count ( 27151647)
  • Alzheimer's disease (survival time) ( 25649651)
  • Breast cancer (survival) ( 25890600)
  • Dimensional psychopathology (Social) ( 29496196)
  • Disease progression in age-related macular degeneration ( 29346644)
  • Formal thought disorder in schizophrenia ( 22648509)
  • Heel bone mineral density ( 30598549)
  • LDL cholesterol levels in HIV infection ( 33109212)
  • Obesity-related traits ( 23251661)
  • Photic sneeze reflex ( 27182965)
  • Prostate cancer ( 29892016)
  • Schizophrenia ( 22688191)
  • Serum uric acid levels in response to allopurinol in gout ( 25676789)
  • Sleep duration ( 25469926)
  • Substance dependence ( 21298047)
  • Testicular germ cell tumor ( 28604728)
Interacting Genes 39 interacting genes: ACTA1 AIMP1 AKAP5 APC CALM1 CDC42 CDH1 CLIC5 CLIP1 CREBBP CTNNB1 CYBB DUX4 EGFR EZR GRIA4 ILF2 KDR LBX1 MAPK1 MEI4 MEN1 MEOX2 MYL1 NPHS1 OTX2 PDLIM7 PKNOX2 PRKACA PTPRM RAC1 S100B STAU1 SUMO2 TEPSIN TSG101 UBE2I VASP YWHAQ 32 interacting genes: ARFIP2 C10orf88 C1orf216 CCDC116 CCDC185 CCDC196 CENPP CREBL2 CSTF2T CTTNBP2 CTTNBP2NL DDA1 ENKD1 FAM110B FHL2 HGS HOXB1 IQGAP1 MBD3 MCRS1 MYO15B NRIP1 NUP54 NUP58 PBX4 PICK1 SMARCD1 STK16 TRIB3 TSG101 USHBP1 VPS37C
Entrez ID 8826 63876
HPRD ID 04541 17857
Ensembl ID ENSG00000140575 ENSG00000165495
Uniprot IDs A0A024RC65 P46940 Q96KN3
PDB IDs 1X0H 2RR8 3FAY 3I6X 5L0O
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?