SUCLG1 and SUCLG2

Number of citations of the paper that reports this interaction (PubMedID 10873456)
24

Data Source:
HPRD (in vitro)

		SUCLG1	SUCLG2
Description		succinate-CoA ligase GDP/ADP-forming subunit alpha	succinate-CoA ligase GDP-forming subunit beta
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix Succinate-CoA Ligase Complex (ADP-forming)	Mitochondrion Mitochondrial Matrix Plasma Membrane Succinate-CoA Ligase Complex Succinate-CoA Ligase Complex (GDP-forming)
	Molecular Function	Nucleotide Binding RNA Binding Succinate-CoA Ligase (ADP-forming) Activity Succinate-CoA Ligase (GDP-forming) Activity Protein Binding	Magnesium Ion Binding Succinate-CoA Ligase (ADP-forming) Activity Succinate-CoA Ligase (GDP-forming) Activity Protein Binding ATP Binding GTP Binding GDP Binding Protein-containing Complex Binding
	Biological Process	Tricarboxylic Acid Cycle	Tricarboxylic Acid Cycle Succinyl-CoA Metabolic Process Succinate Metabolic Process
Pathways		Citric acid cycle (TCA cycle)	Citric acid cycle (TCA cycle)
Drugs			Phenethyl Isothiocyanate
Diseases
GWAS		Coronary artery calcification ( 23870195) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Gut microbiota (functional units) ( 27694959)	Blood metabolite levels ( 24816252) Body mass index ( 28552196) Cerebrospinal AB1-42 levels in Alzheimer's disease dementia ( 25027320) Corneal astigmatism ( 22144915) Diabetic kidney disease ( 26305897) FEV1 ( 30804560) Height ( 20881960) Hip circumference ( 28552196) IgE levels ( 23146381) Lung function (FVC) ( 28166213 30804560) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Metabolite levels ( 23823483) Spontaneous preterm birth with premature rupture of membranes ( 31194736) Thrombin-activatable fibrinolysis inhibitor activation peptide ( 29378355) Urinary metabolite levels in chronic kidney disease ( 31959995)
Interacting Genes		2 interacting genes: CHMP1B SUCLG2	3 interacting genes: GPR143 SGCG SUCLG1
Entrez ID		8802	8801
HPRD ID		18128	06799
Ensembl ID		ENSG00000163541	ENSG00000172340
Uniprot IDs		P53597	Q96I99
PDB IDs		6G4Q 6WCV	6WCV
Enriched GO Terms of Interacting Partners?
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