RIPK1 and FADD

  • Number of citations of the paper that reports this interaction (PubMedID 19524513)
  • 870
  • Data Source:
  • BioGRID (affinity chromatography technology)
  • HPRD (in vivo)

RIPK1

FADD

Description receptor interacting serine/threonine kinase 1 Fas associated via death domain
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Cerebral white matter volume ( 31530798)
  • Depressive symptoms x independent stressful life events interaction (1df test) ( 30718454)
  • Depressive symptoms x independent stressful life events interaction (2df test) ( 30718454)
  • Idiopathic osteonecrosis of the femoral head ( 28000841)
Interacting Genes 52 interacting genes: BIRC3 CASP8 CCDC50 CDC42BPB CFLAR CRADD EGFR FADD FAS GMPR H2BC13 HSP90AA1 IKBKB IKBKE IKBKG ITCH MAP3K1 MAP3K14 MAP3K3 MAP3K8 MTDH NFKB1 NUMBL OTUD1 PDXK PRPF4B PTK2 PXDC1 RIPK3 RNF11 RNF216 SQSTM1 TAX1BP1 TBK1 TICAM1 TNF TNFAIP3 TNFRSF10A TNFRSF10B TNFRSF1A TRADD TRAF1 TRAF2 TRAF3 TRAF5 TRIM38 TRPC4AP UBE2N WRNIP1 YOD1 ZFAND5 ZNHIT1 54 interacting genes: ABCA1 ANK3 ATG5 BTG1 CASP10 CASP8 CASP8AP2 CFLAR CSNK1A1 DAP3 DAPK1 DDIT4L DDX24 DEDD EDA2R FAF1 FAS FASLG HIPK3 IKBKG IRAK1 LRRCC1 MBD4 MKRN1 MOB4 MYD88 NACA NOL3 NUTM2F PARK7 PEA15 PIDD1 PIN1 PRKCZ PTPN13 RALBP1 RAP1A RIPK1 RNF4 RYBP SDCBP STAT1 STUB1 TAB1 TCEA2 TNFRSF10A TNFRSF10B TRADD TRAF2 TRIM21 UBE2I XPO5 ZCCHC12 ZMYM5
Entrez ID 8737 8772
HPRD ID 04583 03909
Ensembl ID ENSG00000137275 ENSG00000168040
Uniprot IDs A0A024QZU0 Q13546 Q13158
PDB IDs 4ITH 4ITI 4ITJ 4NEU 5HX6 5TX5 5V7Z 6AC5 6C3E 6C4D 6HHO 6NW2 6NYH 6OCQ 6R5F 6RLN 1A1W 1A1Z 1E3Y 1E41 2GF5 3EZQ 3OQ9 6ACI
Enriched GO Terms of Interacting Partners?
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