GPAA1 and DGAT1

		GPAA1	DGAT1
Description		glycosylphosphatidylinositol anchor attachment 1	diacylglycerol O-acyltransferase 1
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Endoplasmic Reticulum Endoplasmic Reticulum Membrane Centrosome Cytosol Membrane GPI-anchor Transamidase Complex	Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Membrane Specific Granule Membrane
	Molecular Function	GPI-anchor Transamidase Activity Protein Binding Tubulin Binding GPI Anchor Binding	2-acylglycerol O-acyltransferase Activity Diacylglycerol O-acyltransferase Activity Protein Binding O-acyltransferase Activity Acyltransferase Activity Identical Protein Binding Retinol O-fatty-acyltransferase Activity
	Biological Process	Proteolysis Protein Retention In ER Lumen Attachment Of GPI Anchor To Protein Protein-containing Complex Assembly	Monoacylglycerol Biosynthetic Process Triglyceride Metabolic Process Triglyceride Biosynthetic Process Lipid Storage Very-low-density Lipoprotein Particle Assembly Long-chain Fatty-acyl-CoA Metabolic Process Retinol Metabolic Process Diacylglycerol Metabolic Process Fatty Acid Homeostasis
Pathways		Attachment of GPI anchor to uPAR	Acyl chain remodeling of DAG and TAG Neutrophil degranulation Triglyceride biosynthesis
Drugs
Diseases
GWAS		Asthma ( 31959851) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Serum metabolite concentrations in chronic kidney disease ( 33838163) Serum metabolite levels ( 23093944)	Dupuytren's disease ( 28886342) Fasting glucose ( 34059833)
Interacting Genes		19 interacting genes: ADAMDEC1 AGTR1 AQP2 CACNG8 DGAT1 EIF3E GIT1 GNRHR GRIK5 LRRC14 LY6E NDRG1 PIGK PIGT PIGU PIN1 PRR13 TERF2IP TONSL	4 interacting genes: CCR9 CD1A GABRA4 GPAA1
Entrez ID		8733	8694
HPRD ID		04334	05360
Ensembl ID		ENSG00000197858	ENSG00000185000
Uniprot IDs		O43292	O75907
PDB IDs			6VP0 6VYI 6VZ1
Enriched GO Terms of Interacting Partners?
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