ACTN1 and GRIN2A

  • Number of citations of the paper that reports this interaction (PubMedID 11854440)
  • 11
  • Data Source:
  • HPRD (in vivo)

ACTN1

GRIN2A

Description actinin alpha 1 glutamate ionotropic receptor NMDA type subunit 2A
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885)
  • Bipolar disorder ( 33263727 31043756)
  • Bipolar I disorder ( 31043756)
  • Chronic kidney disease ( 26420894)
  • Clostridioides difficle infection ( 33841421)
  • Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
  • Copper levels ( 26025379)
  • Daytime nap ( 33568662)
  • FEV1 ( 30804560)
  • General risk tolerance (MTAG) ( 30643258)
  • Hallux valgus ( 32131869)
  • Hepatitis B ( 22004137)
  • Laryngeal squamous cell carcinoma ( 25194280)
  • Lung function (FVC) ( 30804560)
  • Metabolite levels ( 23823483)
  • Night sleep phenotypes ( 27126917)
  • Refractive error ( 32231278)
  • Rosacea symptom severity ( 29771307)
  • Schizophrenia ( 28991256 25056061 29483656 30285260)
  • Tenofovir clearance in HIV infection ( 26148204)
  • Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010)
  • Waist circumference adjusted for BMI (smoking interaction) ( 28443625)
Interacting Genes 92 interacting genes: ACTN2 ACTN3 ADORA2A APC APPBP2 ATXN2 ATXN7 C14orf119 CACNA1A CAMK2A CBY2 CDK5 CDK5R1 CDK5R2 CLIC5 COIL COL17A1 CSRP1 CSRP3 CTNNA1 DDIAS DYNLT1 EIF2S1 EPM2AIP1 ERBIN FBP1 FXN FXR1 GADD45G GFI1B GIPC1 GIT2 GRIA4 GRIN2A GRM5 GTF2H1 HSPB1 ICAM5 ITGB1 KAT2B KCTD6 KPNA2 LINC01554 LNX1 LPP MAGEA11 MAP2 MAP3K1 MED14 MICALL2 MTDH MTNR1A MTNR1B MYOT MYOZ1 MYOZ2 MYOZ3 NEBL NKAPD1 NR1H3 NUMBL OAS1 PALLD PDHX PDLIM1 PDLIM5 PIAS4 PKD1 PKN1 PLD2 PSEN1 PSMA1 PTK2 PTPN1 PTPN6 PYGB RAVER1 RPS27 SIRPA SLC2A4 SORBS2 SRC SSX2IP SYNPO2L TES TSC1 TTN TXN USP2 VCL XRCC4 ZYX 41 interacting genes: ACOT8 ACTN1 AKT1 AP1M1 AP2M1 AP4M1 ARHGAP32 CAMK2A CAMK2B CARHSP1 CASK CDK5 CSNK2A1 CSNK2A2 CSNK2B DLG1 DLG2 DLG3 DLG4 DLGAP1 EML1 FYN GRIN1 GRIN2B GRIN3A GRIN3B ID4 IL16 NEDD4 PATJ PCDH8 PLA2G10 PLCG1 PRKCA PRM1 PTK2B PTPN4 RGS3 RNF40 SPTAN1 SRC
Entrez ID 87 2903
HPRD ID 00020 00698
Ensembl ID ENSG00000072110 ENSG00000183454
Uniprot IDs A0A024R694 A0A7I2V4Y4 P12814 A0A6Q8PGD2 Q12879 Q547U9 Q59EW6
PDB IDs 2EYI 2EYN 2N8Y 2N8Z 3NFL 5H8F 5H8H 5H8N 5H8Q 5I2K 5I2N 5KCJ 5KDT 5TP9 5TPA 6IRA 6IRF 6IRG 6IRH
Enriched GO Terms of Interacting Partners?
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