S1PR4 and GEMIN4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		S1PR4	GEMIN4
Description		sphingosine-1-phosphate receptor 4	gem nuclear organelle associated protein 4
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Plasma Membrane Integral Component Of Plasma Membrane	Nucleoplasm Nucleolus Cytoplasm Cytosol Cajal Body Membrane Nuclear Body Small Nuclear Ribonucleoprotein Complex SMN Complex SMN-Sm Protein Complex Extracellular Exosome Gemini Of Coiled Bodies
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding Lipid Binding Sphingosine-1-phosphate Receptor Activity	Protein Binding Ribonucleoprotein Complex Binding
	Biological Process	Sphingosine-1-phosphate Receptor Signaling Pathway Immune Response G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Activation Of Phospholipase C Activity Positive Regulation Of Cytosolic Calcium Ion Concentration Regulation Of Metabolic Process	Spliceosomal SnRNP Assembly RRNA Processing
Pathways		G alpha (i) signalling events Lysosphingolipid and LPA receptors	snRNP Assembly
Drugs		Fingolimod
Diseases
GWAS		Asthma ( 31959851) Basophil percentage of granulocytes ( 27863252) Eosinophil counts ( 32888494 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 32888494 27863252) Granulocyte count ( 27863252) Granulocyte percentage of myeloid white cells ( 27863252) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Lymphocyte counts ( 32888494) Lymphocyte percentage of white cells ( 27863252) Mean platelet volume ( 32888494) Monocyte count ( 32888494 27863252) Monocyte percentage of white cells ( 32888494 27863252) Myeloid white cell count ( 27863252) Neutrophil count ( 27863252) Neutrophil percentage of granulocytes ( 27863252) Neutrophil percentage of white cells ( 32888494 27863252) Plateletcrit ( 32888494) Reticulocyte fraction of red cells ( 32888494) Sum basophil neutrophil counts ( 27863252) Sum eosinophil basophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) White blood cell count ( 29403010 32888494 27863252)	Prostate cancer ( 23535732)
Interacting Genes		5 interacting genes: GEMIN4 GNA12 GNA13 GNAI1 TNFSF14	55 interacting genes: AGO2 ALPP CALCOCO2 CCDC185 CCT3 CDC20B CERCAM CFP DDX20 DHX9 DMPK FBXL12 FLAD1 GEMIN5 GLYR1 HR KANK2 KARS1 KRTAP13-2 KRTAP13-4 KRTAP15-1 KRTAP2-3 KRTAP2-4 KRTAP9-2 LGALS1 LGALS3 LY86 MORC4 NPPB NUFIP1 PIAS3 PSMB1 PTCD1 PTEN RAD51D RN7SL1 RNU1-1 RNU2-1 S1PR4 SNRPB SNRPD1 SNRPD2 SPG21 SPRY1 SQSTM1 SRRT STXBP2 STXBP3 TAP1 TOP1 UFC1 USP15 USP2 ZNF326 ZNF35
Entrez ID		8698	50628
HPRD ID		04779	07370
Ensembl ID		ENSG00000125910	ENSG00000179409
Uniprot IDs		O95977	I3L2C7 P57678 Q8WUM5
PDB IDs		2DCO
Enriched GO Terms of Interacting Partners?
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