PEA15 and PGM1

Number of citations of the paper that reports this interaction (PubMedID 24710276)
4

Data Source:
BioGRID (two hybrid)

		PEA15	PGM1
Description		proliferation and apoptosis adaptor protein 15	phosphoglucomutase 1
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GO Annotations	Cellular Component	Nucleoplasm Cytosol Microtubule Associated Complex	Extracellular Region Cytoplasm Cytosol Extracellular Exosome Tertiary Granule Lumen Ficolin-1-rich Granule Lumen
	Molecular Function	Protein Binding	Magnesium Ion Binding Phosphoglucomutase Activity Protein Binding
	Biological Process	MAPK Cascade Apoptotic Process Carbohydrate Transport Response To Morphine Negative Regulation Of Glucose Import Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors	Carbohydrate Metabolic Process Glucose Metabolic Process Gluconeogenesis Glycolytic Process
Pathways		RAF-independent MAPK1/3 activation RAF/MAP kinase cascade	Glycogen synthesis Defective PGM1 causes PGM1-CDG (CDG1t) Neutrophil degranulation
Drugs			Alpha-D-Glucose 1,6-Bisphosphate Alpha-D-Glucose-1-Phosphate-6-Vanadate
Diseases
GWAS			Alcohol consumption (transferrin glycosylation) ( 21665994) Blood protein levels ( 29875488) Type 1 diabetes ( 32005708 19430480 33830302 34012112 34127860) Type 2 diabetes ( 32499647)
Interacting Genes		40 interacting genes: ABCD4 AK9 AKT1 ATP1B3 CACYBP CAMK2G CASP8 CEP120 COPS5 DNAJB1 DYRK1A FADD HTRA2 KLHL12 L1CAM LUC7L2 MAPK1 MAPK3 MTIF3 OSBPL1A PANK4 PDE4DIP PDPK1 PGM1 PLD1 PLD2 PPP4R3A PRKCA PUS3 RAMAC RPS6KA3 RPSA RSL24D1 SNRPG SON TALDO1 TENT4B TERF2IP TJP1 TRAPPC13	19 interacting genes: APP CHAF1B DNAJB6 ENO3 HSPB2 KIF1B LINC01554 NLRP3 OGT PAXIP1 PEA15 POT1 S100A1 S100B TERF1 TERF2IP TINF2 USP4 XRN2
Entrez ID		8682	5236
HPRD ID		04579	01389
Ensembl ID		ENSG00000162734	ENSG00000079739
Uniprot IDs		B1AKZ4 B1AKZ5 Q15121 Q96FS5	B4DDQ8 B7Z6C2 P36871
PDB IDs		4IZ5 4IZA 6P6B 6P6C	5EPC 5F9C 5HSH 5JN5 5TR2 5VBI 5VEC 5VG7 5VIN 6SNO 6SNP 6SNQ 6UIQ 6UO6
Enriched GO Terms of Interacting Partners?
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