OASL and MBD1

Number of citations of the paper that reports this interaction (PubMedID 14728690)
8

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		OASL	MBD1
Description		2'-5'-oligoadenylate synthetase like	methyl-CpG binding domain protein 1
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GO Annotations	Cellular Component	Nucleoplasm Nucleolus Cytoplasm Cytosol Membrane	Chromatin Nucleus Nucleoplasm Cytoplasm Nuclear Matrix Nuclear Speck
	Molecular Function	2'-5'-oligoadenylate Synthetase Activity DNA Binding RNA Binding Double-stranded RNA Binding Protein Binding Thyroid Hormone Receptor Binding	DNA Binding Chromatin Binding Protein Binding Zinc Ion Binding Methyl-CpG Binding Double-stranded Methylated DNA Binding Unmethylated CpG Binding
	Biological Process	Response To Virus Negative Regulation Of Viral Genome Replication Innate Immune Response Defense Response To Virus Regulation Of Ribonuclease Activity Interleukin-27-mediated Signaling Pathway Positive Regulation Of RIG-I Signaling Pathway	Transcription By RNA Polymerase II Heart Development Aging Response To Xenobiotic Stimulus Negative Regulation Of Gene Expression Neuron Differentiation Response To Nutrient Levels Response To Estradiol Response To Cocaine Regulation Of DNA Methylation Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Astrocyte Differentiation
Pathways		Interferon gamma signaling OAS antiviral response Interferon alpha/beta signaling	SUMOylation of transcription cofactors
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 33547301) C-reactive protein ( 22939635) C-reactive protein levels ( 24763700 30388399) Cardiovascular disease risk factors ( 21943158) Hematocrit ( 32888494) Hemoglobin ( 32888494) N-glycan levels ( 21908519 21203500) Serum metabolite levels ( 23093944) Type 2 diabetes ( 30054458)	Chronic lymphocytic leukemia ( 28165464)
Interacting Genes		3 interacting genes: MBD1 SEZ6L2 THRA	45 interacting genes: APP ATF7IP ATF7IP2 ATXN1L C1QBP CBX4 CBX5 CCDC136 CHAF1A COPE DVL3 ECT2 EEF1G GRN HDAC3 HIPK3 HTT JAG2 LTBP3 LTBP4 MDFI MEGF6 NELL1 NELL2 NOTCH1 NOTCH3 OASL PIAS1 PIAS2 POMGNT1 RNF2 SETDB1 SLC25A3 SMAD1 SMAD3 SMAD5 SMAD7 SMAD9 SNAPC2 SP1 SUV39H1 TENM1 TNC ZNF384 ZNF512B
Entrez ID		8638	4152
HPRD ID		04473	01133
Ensembl ID		ENSG00000135114	ENSG00000141644
Uniprot IDs		Q15646	A8K654 B4DI41 B4DUR3 Q9UIS9
PDB IDs		1WH3 4XQ7	1D9N 1IG4 4D4W 5W9Q 6D1T
Enriched GO Terms of Interacting Partners?
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