RGS20 and PTPMT1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		RGS20	PTPMT1
Description		regulator of G protein signaling 20	protein tyrosine phosphatase mitochondrial 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Trans-Golgi Network Plasma Membrane	Nucleus Mitochondrion Mitochondrial Inner Membrane
	Molecular Function	GTPase Activity GTPase Activator Activity Protein Binding	Phosphatidylinositol-4,5-bisphosphate 5-phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding Protein Tyrosine/serine/threonine Phosphatase Activity Phosphatidylglycerophosphatase Activity Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity
	Biological Process	G Protein-coupled Receptor Signaling Pathway Regulation Of G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Signal Transduction Regulation Of Catalytic Activity	Cardiolipin Biosynthetic Process Peptidyl-tyrosine Dephosphorylation Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways		G alpha (i) signalling events G alpha (i) signalling events G alpha (z) signalling events G alpha (z) signalling events	Synthesis of PG
Drugs
Diseases
GWAS		Cerebrospinal fluid beta-site APP cleaving enzyme levels ( 29751835) Chronic obstructive pulmonary disease ( 32222710) Serum uric acid levels ( 29559957) Urinary albumin-to-creatinine ratio ( 26631737)	Alzheimer's disease or fasting glucose levels (pleiotropy) ( 30805717) Bipolar disorder ( 31043756) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain morphology (MOSTest) ( 32665545) Estimated glomerular filtration rate ( 30604766) Fruit consumption ( 32066663) Glomerular filtration rate ( 29403010) Hypertension ( 27618448) Loneliness ( 29970889) Loneliness (MTAG) ( 29970889) Mean arterial pressure ( 27618448) Mood instability ( 31168069) Neuroticism ( 29255261) Serum metabolite levels ( 31636271) Serum metabolite levels (CMS) ( 31636271)
Interacting Genes		54 interacting genes: ABHD17A ADRB2 ALPP AQP1 CATSPER1 COL8A1 CRCT1 CREB5 FASLG GLRX3 GNAI1 GNAI2 GNAI3 GNAO1 GNAZ HOXA1 HRG HSPD1 INS KIF1A KLHL38 KRTAP4-2 KRTAP5-11 KRTAP5-6 KRTAP5-9 KRTAP9-3 KRTAP9-8 LCE1A LCE1B LCE1F LCE2A LCE2B LCE2C LCE2D LCE3A LCE3C LCE3D LCE3E LCE4A LCE5A LNX1 MAPKBP1 NECTIN2 NECTIN3 NEK8 NUFIP2 OSTM1 OTX1 PTGER3 PTPMT1 RANBP3 STMN2 TBC1D16 VASN	32 interacting genes: ADAMTSL4 CREB3L1 CYSRT1 GRN KRT31 KRT34 KRT40 KRTAP1-3 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP2-4 KRTAP3-1 KRTAP4-12 KRTAP5-7 KRTAP5-9 KRTAP9-2 KRTAP9-3 LCE2C MAPK6 MDFI MTUS2 NBPF19 NOTCH2NLA RGS20 SIAH1 SSC4D TAB1 TMEM14B TRIM27
Entrez ID		8601	114971
HPRD ID		06225	15151
Ensembl ID		ENSG00000147509	ENSG00000110536
Uniprot IDs		B3KSW4 H9NIM5 O76081	Q8WUK0
PDB IDs
Enriched GO Terms of Interacting Partners?
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