MBD3L1 and MPPED2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		MBD3L1	MPPED2
Description		methyl-CpG binding domain protein 3 like 1	metallophosphoesterase domain containing 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus
	Molecular Function	Protein Binding	Protein Binding Phosphoric Diester Hydrolase Activity AMP Binding GMP Binding Manganese Ion Binding
	Biological Process
Pathways
Drugs
Diseases
GWAS			Adventurousness ( 30643258) Apolipoprotein B levels ( 32203549) Asthma ( 27611488) Automobile speeding propensity ( 30643258) Blood urea nitrogen levels ( 29403010) Chronic kidney disease ( 22479191 26831199) Chronotype ( 30696823) Creatinine levels ( 29403010) Dental caries ( 21940522) Estimated glomerular filtration rate ( 31015462 30604766) Falling risk ( 32999390) Glomerular filtration rate ( 27588450 29403010) Glomerular filtration rate (creatinine) ( 28452372 26831199) Glomerular filtration rate in non diabetics (creatinine) ( 26831199) HDL cholesterol levels ( 32203549) Hip circumference adjusted for BMI ( 34021172) Major depressive disorder ( 27479909) Medication use (diuretics) ( 31015401) Migraine ( 27322543) Morning person ( 30696823) Pit-and-Fissure caries ( 24556642) PR interval ( 32439900) Refractive error ( 32231278) Renal function-related traits (eGRFcrea) ( 22797727) Renal function-related traits (sCR) ( 22797727) Serum uric acid levels ( 30993211 29403010) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Systolic blood pressure ( 30578418) Triglyceride levels ( 32203549) Urate levels ( 31578528)
Interacting Genes		46 interacting genes: ANKS1A BOLA2 BOLA2B C1orf109 C1orf74 CLCNKA CLIC3 CTNNA3 DTX2 EFHC1 EXOC8 FAM124B FHL2 FNDC3B FRS3 GATAD2A GPSM3 GTPBP3 IL16 KCTD9 KIFC3 LMO1 LMO3 MAD2L2 MBD2 MBD3 MLH1 MPPED2 NDUFAF3 NEK6 NXF1 SH2D4A SNAPC5 SNRPB STX11 SUOX TIMM29 TRAPPC2 TRAPPC2B TSGA10 TSGA10IP TSSK3 UBL5 USP20 ZNF76 ZNF77	16 interacting genes: BDNF BEX4 CAGE1 FAM72A GCH1 HOOK2 IKZF1 MBD3L1 NOTCH3 NUP93 PAX6 POMP RIBC1 RXRG TRIP13 VAC14
Entrez ID		85509	744
HPRD ID		12138	02947
Ensembl ID		ENSG00000170948	ENSG00000066382
Uniprot IDs		Q8WWY6	Q15777
PDB IDs
Enriched GO Terms of Interacting Partners?
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