EAF1 and ELL3

Number of citations of the paper that reports this interaction (PubMedID 28514442)
406

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		EAF1	ELL3
Description		ELL associated factor 1	elongation factor for RNA polymerase II 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Transcription Elongation Factor Complex Cajal Body Nuclear Body Nuclear Speck Super Elongation Complex Intracellular Membrane-bounded Organelle Intercellular Bridge	Nucleus Nucleoplasm Chromosome Nucleolus Cytosol Transcription Elongation Factor Complex Nuclear Speck Cell Junction
	Molecular Function	Transcription Elongation Regulator Activity Protein Binding	Cis-regulatory Region Sequence-specific DNA Binding Protein Binding
	Biological Process	Regulation Of Transcription Elongation From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated	DNA-templated Transcription, Elongation Transcription By RNA Polymerase II Transcription Elongation From RNA Polymerase II Promoter Spermatogenesis Regulation Of Epithelial To Mesenchymal Transition Positive Regulation Of DNA-templated Transcription, Elongation SnRNA Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II Stem Cell Differentiation Positive Regulation Of Neurogenesis Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Positive Regulation Of Neural Precursor Cell Proliferation
Pathways		Formation of RNA Pol II elongation complex RNA Polymerase II Pre-transcription Events RNA Polymerase II Transcription Elongation	RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes
Drugs
Diseases
GWAS
Interacting Genes		53 interacting genes: AP2M1 APP ARID4B BEND7 BHLHB9 CCDC150 CCDC33 CEP70 CEP76 DNTTIP1 DPPA4 ELL ELL2 ELL3 FAM228A GADD45GIP1 GAS8 GCSAML GOLGA6L9 GRHL3 GTF2H1 GTF2H4 HOMER3 HSF2BP KEAP1 KIAA1328 MAB21L3 MIPOL1 NUMB PAX6 PICK1 PIH1D1 PSME3 RYBP SDCBP SEMG1 SH3RF1 SRP14 STAC3 TCEA2 TFCP2 TFPT TLE5 TNFAIP8 TNNI1 TRAF2 TRIM62 VAX1 YAF2 ZBTB14 ZNF143 ZNF202 ZNF620	3 interacting genes: EAF1 FTH1 TP53
Entrez ID		85403	80237
HPRD ID		12209	10933
Ensembl ID		ENSG00000144597	ENSG00000128886
Uniprot IDs		Q96JC9	Q9HB65
PDB IDs
Enriched GO Terms of Interacting Partners?
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