DGKZ and POLR2M

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		DGKZ	POLR2M
Description		diacylglycerol kinase zeta	RNA polymerase II subunit M
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Plasma Membrane Postsynaptic Density Nuclear Speck Lamellipodium Glutamatergic Synapse	Intracellular Anatomical Structure Nuclear Envelope RNA Polymerase II, Core Complex RNA Polymerase II, Holoenzyme Neuronal Cell Body
	Molecular Function	NAD+ Kinase Activity Diacylglycerol Kinase Activity Protein Binding ATP Binding Kinase Activity Metal Ion Binding	DNA-directed 5'-3' RNA Polymerase Activity
	Biological Process	Phosphatidic Acid Biosynthetic Process Protein Kinase C-activating G Protein-coupled Receptor Signaling Pathway Cell Migration Platelet Activation Intracellular Signal Transduction Diacylglycerol Metabolic Process Glycerolipid Metabolic Process Lipid Phosphorylation Negative Regulation Of T Cell Receptor Signaling Pathway Regulation Of Synaptic Transmission, Glutamatergic Positive Regulation Of 1-phosphatidylinositol-4-phosphate 5-kinase Activity	RNA Biosynthetic Process Intracellular Signal Transduction Maintenance Of ER Location
Pathways		Effects of PIP2 hydrolysis
Drugs		alpha-Tocopherol succinate
Diseases
GWAS		Age at first sexual intercourse ( 34211149) Alzheimer's disease or fasting glucose levels (pleiotropy) ( 30805717) Autism spectrum disorder or schizophrenia ( 28540026) Body size at age 10 ( 32376654) Immunoglobulin A ( 20694011) Reaction time ( 29844566) Schizophrenia ( 28991256 29483656)	Body mass index ( 28552196) Seasonality ( 25562672)
Interacting Genes		19 interacting genes: DMD HRAS LEPR MAPK6 PLCG1 POLR2M PRKCA RASGRP1 RB1 RBL1 RBL2 SAT1 SNTA1 SNTB1 SNTB2 SNTG1 SNX27 SRC TP53	22 interacting genes: AHSP ANKHD1 APOD CEBPG CEP126 DAPK1 DGKZ HIGD1B LRRK1 LRRK2 MYO3A MYO9A NEDD4 PSMC2 RBM4B RPL7A SCMH1 SIVA1 THAP1 UQCRQ WDR89 ZNF410
Entrez ID		8525	81488
HPRD ID		03260	07575
Ensembl ID		ENSG00000149091	ENSG00000255529
Uniprot IDs		Q13574	P0CAP1 P0CAP2 Q6EEV4
PDB IDs		5ELQ	2KXS 6DRD
Enriched GO Terms of Interacting Partners?
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