PKP4 and DSC3

Number of citations of the paper that reports this interaction (PubMedID 12615965)
19

Data Source:
HPRD (in vitro, two hybrid)

		PKP4	DSC3
Description		plakophilin 4	desmocollin 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Spindle Pole Cornified Envelope Nucleus Cytoplasm Cytoskeleton Plasma Membrane Cell-cell Junction Adherens Junction Cytoplasmic Side Of Plasma Membrane Postsynaptic Density Cell Junction Desmosome Midbody Cell-cell Contact Zone Perinuclear Region Of Cytoplasm Spindle Midzone Mitotic Spindle	Cornified Envelope Plasma Membrane Cell-cell Junction Membrane Integral Component Of Membrane Cell Junction Desmosome
	Molecular Function	Protein Binding Cadherin Binding	Calcium Ion Binding Gamma-catenin Binding
	Biological Process	Cell-cell Junction Assembly Cell-cell Signaling Regulation Of Cell Adhesion Positive Regulation Of Cytokinesis Positive Regulation Of GTPase Activity Cell-cell Adhesion	Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Cell-cell Adhesion
Pathways		Keratinization Formation of the cornified envelope RND3 GTPase cycle RND2 GTPase cycle RND1 GTPase cycle	Keratinization Formation of the cornified envelope
Drugs
Diseases
GWAS		Borderline personality disorder ( 28632202) Obesity-related traits ( 23251661) Restless legs syndrome ( 29029846)	Bronchopulmonary dysplasia ( 23897914) Hand grip strength (Mahalanobis distance) ( 32235003) Metabolite levels ( 31628463) Obesity-related traits ( 23251661) Protein quantitative trait loci ( 18464913) Supraventricular ectopy ( 29618737) Type 2 diabetes ( 31049640)
Interacting Genes		22 interacting genes: ARMC8 ATPAF2 CDH1 CDH2 CDH5 DSC3 DSP ERBIN GABARAP GOLGA2 LNX1 LZTS2 MINK1 OGT OSGEP PAXIP1 PDZD2 PGAM1 PSEN1 SCN2A TRIM23 UBASH3B	7 interacting genes: CTNNB1 DDX10 DSC2 JUP PKP3 PKP4 UCHL5
Entrez ID		8502	1825
HPRD ID		05043	02604
Ensembl ID		ENSG00000144283	ENSG00000134762
Uniprot IDs		Q99569	Q14574
PDB IDs
Enriched GO Terms of Interacting Partners?
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