FAM83A and GPSM1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		FAM83A	GPSM1
Description		family with sequence similarity 83 member A	G protein signaling modulator 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Golgi Membrane Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Cell Cortex Protein-containing Complex
	Molecular Function	Protein Binding Protein Kinase Binding Phosphatidylinositol 3-kinase Regulatory Subunit Binding Identical Protein Binding	GDP-dissociation Inhibitor Activity Protein Binding
	Biological Process	Signal Transduction Epidermal Growth Factor Receptor Signaling Pathway Cell Population Proliferation	Nervous System Development Positive Regulation Of Macroautophagy Cell Differentiation Negative Regulation Of GTPase Activity Negative Regulation Of Guanyl-nucleotide Exchange Factor Activity
Pathways			G alpha (i) signalling events
Drugs
Diseases
GWAS		Urinary uromodulin levels ( 24578125)	Acute insulin response (insulin secretion adjusted) ( 28490609) Birth weight ( 31043758) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Insulinogenic index ( 23263489) Joint damage in rheumatoid arthritis ( 26498133) Myocardial infarction ( 33532862) Offspring birth weight ( 31043758) Type 2 diabetes ( 30297969 29632382 26818947 23945395 31118516 32499647 30718926 28869590) Type 2 diabetes (adjusted for BMI) ( 29632382) Ulcerative colitis ( 28067908) White blood cell count ( 29403010)
Interacting Genes		23 interacting genes: BHLHE40 CYSRT1 DAZAP2 FOXH1 FOXI1 GCC1 GPSM1 KRT34 KRTAP6-2 KRTAP6-3 KRTAP8-1 MAGED1 MGAT5B NCK2 PLAGL2 PPP1R16B PRDM14 PSMA3 QARS1 SMYD1 TRIM23 TRIM27 UBASH3A	28 interacting genes: BHLHE40 CCDC158 CTDSP1 DAZAP2 DCAF11 DMRT3 FAM161B FAM83A FAM90A1 FXR2 GCM2 GLIS2 GNAI1 GNAI3 HMG20A INSC KANK2 MAP1LC3A OSTM1 RIBC1 SEPTIN1 TASOR2 TEKT4 TRIP13 USHBP1 USP9X VEZF1 ZBED1
Entrez ID		84985	26086
HPRD ID		17489	17075
Ensembl ID		ENSG00000147689	ENSG00000160360
Uniprot IDs		Q86UY5	A0A087WVF5 A0A0A0MRC4 A0A0A0MSK4 Q86YR5
PDB IDs		4URJ
Enriched GO Terms of Interacting Partners?
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