TOX2 and UNC5CL

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TOX2	UNC5CL
Description		TOX high mobility group box family member 2	unc-5 family C-terminal like
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Cytoplasm Membrane Integral Component Of Membrane
	Molecular Function	Transcription Coactivator Activity Chromatin DNA Binding	Netrin Receptor Activity Protein Binding Peptidase Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II	Proteolysis Netrin-activated Signaling Pathway Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of JNK Cascade
Pathways
Drugs
Diseases
GWAS		Attention deficit hyperactivity disorder (inattention symptoms) ( 32595297) Colorectal cancer ( 30529582) Conduct disorder (symptom count) ( 20585324) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494 27863252) Mean spheric corpuscular volume ( 32888494) Multiple sclerosis ( 31604244) Neutrophil count ( 32888494) Post bronchodilator FEV1/FVC ratio in COPD ( 26634245) Red blood cell count ( 32888494 27863252) Refractive error ( 32231278) White blood cell count ( 32888494)	Alzheimer's disease or family history of Alzheimer's disease ( 33589840) Esophageal cancer ( 21642993) Gastric cancer ( 26129866) Non-cardia gastric cancer ( 26129866) Urate levels ( 31578528)
Interacting Genes		24 interacting genes: ANKS1A APP CENPP CSTF2T ENKD1 HCK HOMER3 HSF2BP HSFY1 HSFY2 LGALS4 MFHAS1 NDUFAB1 P4HA3 PHF1 RIBC1 SPG21 TCEA2 TEKT4 TEKT5 TLX3 UNC5CL YPEL3 ZNF461	7 interacting genes: KRTAP13-2 KRTAP6-1 NFKB1 PGAM1 RELA TOX2 ZMYND12
Entrez ID		84969	222643
HPRD ID		12734	09844
Ensembl ID		ENSG00000124191	ENSG00000124602
Uniprot IDs		Q96NM4	H8YHX0 Q8IV45
PDB IDs
Enriched GO Terms of Interacting Partners?
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