FBH1 and PIM2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
HPRD (two hybrid)

		FBH1	PIM2
Description		F-box DNA helicase 1	Pim-2 proto-oncogene, serine/threonine kinase
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus SCF Ubiquitin Ligase Complex	Cytoplasm
	Molecular Function	DNA Helicase Activity Double-stranded DNA Binding Single-stranded DNA Binding Protein Binding ATP Binding DNA Translocase Activity ATP Hydrolysis Activity 3'-5' DNA Helicase Activity	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity
	Biological Process	Double-strand Break Repair Via Homologous Recombination Recombinational Repair DNA Catabolic Process, Endonucleolytic Positive Regulation Of Protein Phosphorylation Cellular Response To DNA Damage Stimulus Cell Death Protein Ubiquitination Replication Fork Processing DNA Duplex Unwinding Negative Regulation Of Chromatin Binding Replication Fork Protection Response To Intra-S DNA Damage Checkpoint Signaling Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Negative Regulation Of Double-strand Break Repair Via Homologous Recombination	G1/S Transition Of Mitotic Cell Cycle Protein Phosphorylation Apoptotic Process Regulation Of Mitotic Cell Cycle Negative Regulation Of Cell Population Proliferation Response To Virus Positive Regulation Of Autophagy Negative Regulation Of Apoptotic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Transcription, DNA-templated Protein Autophosphorylation Protein Stabilization
Pathways
Drugs
Diseases
GWAS
Interacting Genes		9 interacting genes: CUL1 ESR1 PIM2 RAD51 RBX1 RPL13A SKP1 UBC ZDHHC17	16 interacting genes: ATXN1 BAD CUTC DAPK1 FBH1 FBP1 FBXO7 GSK3B HNRNPH3 HSF1 IKBKG NDUFB8 RPL21 SOCS1 TRIM14 ZNF821
Entrez ID		84893	11040
HPRD ID		06243	02244
Ensembl ID		ENSG00000134452	ENSG00000102096
Uniprot IDs		B3KV95 F6UZG9 Q2TAK1 Q8NFZ0	A0A024QYW7 Q9P1W9
PDB IDs			2IWI 4X7Q
Enriched GO Terms of Interacting Partners?
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