CRACR2A and FKBP6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CRACR2A	FKBP6
Description		calcium release activated channel regulator 2A	FKBP prolyl isomerase family member 6 (inactive)
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GO Annotations	Cellular Component	Golgi Membrane Immunological Synapse Extracellular Region Cytoplasm Microtubule Organizing Center Cytoskeleton Plasma Membrane Membrane Trans-Golgi Network Membrane Weibel-Palade Body Specific Granule Lumen	Synaptonemal Complex Cytoplasm Cytosol
	Molecular Function	GTPase Activity Calcium Ion Binding Protein Binding GTP Binding	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding FK506 Binding Identical Protein Binding Hsp90 Protein Binding
	Biological Process	Store-operated Calcium Entry Adaptive Immune Response Activation Of Store-operated Calcium Channel Activity T-helper 1 Cell Differentiation Positive Regulation Of JNK Cascade Positive Regulation Of Calcium Ion Transport	Protein Folding Spermatogenesis Cell Differentiation Gene Silencing By RNA PiRNA Metabolic Process DNA Methylation Involved In Gamete Generation Positive Regulation Of Viral Genome Replication Meiotic Cell Cycle
Pathways		Neutrophil degranulation	Meiotic synapsis PIWI-interacting RNA (piRNA) biogenesis
Drugs
Diseases
GWAS			Height ( 31562340) Immune reponse to smallpox (secreted IL-12p40) ( 22610502)
Interacting Genes		35 interacting genes: ANKRD29 ASB3 ATN1 CCHCR1 CDC23 DDIT3 FAM156A FAM156B FAM86C1P FKBP6 GIGYF1 GOLGA2 KRT31 KRT75 KRTAP13-1 KRTAP19-5 LRIF1 MDFI MID2 MKRN3 NOTCH2NLA OIP5 PNMA5 POLR1C RBAK RORB SLAIN1 SORBS3 TLE5 TRAF1 TRIM29 USP2 ZC2HC1C ZNF20 ZNF655	37 interacting genes: ACD ALDH3A1 CCDC198 CCNK CDK5RAP3 CFP CRACR2A DDIT4L DLGAP4 ECM1 EEF1D ENKD1 FAM107A GAPDH GSC2 HSP90AA1 IHO1 KANK2 KRT75 LZTS2 MAP3K1 MEI4 MEOX2 NME7 NTAQ1 PIAS2 PICK1 PPP1R32 RAB11FIP2 RNF4 SUMO1P1 TEPSIN TINF2 TMEM9B TRIM55 TRIM63 ZNF655
Entrez ID		84766	8468
HPRD ID		10079	05326
Ensembl ID		ENSG00000130038	ENSG00000077800
Uniprot IDs		Q9BSW2	A0A3B3IST2 O75344
PDB IDs		6PSD	3B7X
Enriched GO Terms of Interacting Partners?
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