PCGF1 and FCHO1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PCGF1	FCHO1
Description		polycomb group ring finger 1	FCH and mu domain containing endocytic adaptor 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm PcG Protein Complex PRC1 Complex	Nucleoplasm Cytoplasm Cytosol Plasma Membrane Clathrin-coated Pit Clathrin-coated Vesicle
	Molecular Function	Protein Binding Protein C-terminus Binding Metal Ion Binding Promoter-specific Chromatin Binding	Protein Binding AP-2 Adaptor Complex Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Histone H2A Monoubiquitination Histone H2A-K119 Monoubiquitination	Clathrin Coat Assembly Clathrin-dependent Endocytosis
Pathways			Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs
Diseases
GWAS			Basophil count ( 32888494) Coronary artery disease ( 29212778) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Monocyte percentage of white cells ( 32888494) Myocardial infarction ( 33532862)
Interacting Genes		10 interacting genes: CALCOCO2 CBX7 CD244 FCHO1 H2AC4 MUC7 RNF125 TRIM55 UBE2D3 UBE2U	52 interacting genes: ACVR1 APP BYSL CCDC13 CSNK2A1 CWF19L2 DAB2 DDX6 DNAJC5 ELOA EPS15 EPS15L1 EXOSC5 FBXL7 GDF15 GRB7 GUCD1 ITSN1 KAT5 KPRP KRTAP10-1 KRTAP10-5 KRTAP13-2 KRTAP13-4 KRTAP15-1 KRTAP4-12 KRTAP6-1 KRTAP6-3 LGALS14 MAB21L3 NCK1 PCGF1 PHETA1 PHLDA2 PICALM PLAC8 PLSCR4 PRPF3 PRPH PTK6 SH2D4A SMURF1 SRPK2 SYTL4 TCEA2 TCEANC TGFB1 TRIM42 TSPAN4 ZBTB16 ZBTB24 ZNF688
Entrez ID		84759	23149
HPRD ID		11404	16887
Ensembl ID		ENSG00000115289	ENSG00000130475
Uniprot IDs		Q9BSM1	A0A0C3SFZ9 B7ZAZ3 O14526
PDB IDs		4HPL 4HPM 5JH5
Enriched GO Terms of Interacting Partners?
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