SMARCA5 and RSF1

Number of citations of the paper that reports this interaction (PubMedID 12972596)
43

Data Source:
HPRD (in vivo)

		SMARCA5	RSF1
Description		SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5	remodeling and spacing factor 1
Image			No pdb structure
GO Annotations	Cellular Component	Condensed Chromosome Fibrillar Center Nucleus Nucleoplasm Chromatin Silencing Complex Cytosol NURF Complex RSF Complex Intracellular Membrane-bounded Organelle Nuclear Replication Fork	Nucleus Nucleoplasm RSF Complex
	Molecular Function	DNA Binding Helicase Activity Protein Binding ATP Binding ATP-dependent Activity, Acting On DNA Hydrolase Activity ATP Hydrolysis Activity Nucleosome Binding Histone Binding ATP-dependent Chromatin Remodeler Activity	Transcription Coregulator Activity Protein Binding ATP Hydrolysis Activity Histone Binding Metal Ion Binding
	Biological Process	RDNA Heterochromatin Assembly Nucleosome Assembly Chromatin Remodeling DNA-templated Transcription, Initiation Regulation Of Transcription By RNA Polymerase II Nucleosome Positioning Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Leukemia Inhibitory Factor	Nucleosome Assembly Chromatin Remodeling DNA-templated Transcription, Initiation Nucleosome Positioning Negative Regulation Of DNA Binding Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Viral Transcription
Pathways		NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks Deposition of new CENPA-containing nucleosomes at the centromere	Deposition of new CENPA-containing nucleosomes at the centromere
Drugs		Beta-D-Glucose 4-Deoxy-Alpha-D-Glucose
Diseases
GWAS		Height ( 31562340) Malaria ( 31844061)	Left-handedness ( 32989287) Tourette syndrome ( 30818990)
Interacting Genes		19 interacting genes: BAZ1A BAZ1B BAZ2A CDT1 CHRAC1 CREB1 CTNNB1 DNMT3B GSK3A H3-3A H3C1 H4-16 HDAC2 MAF POLE3 PTEN RAD21 RSF1 SATB1	6 interacting genes: ALG8 CSNK2A1 HMGB1 NFKB1 SMARCA5 TENM4
Entrez ID		8467	51773
HPRD ID		04538	10537
Ensembl ID		ENSG00000153147	ENSG00000048649
Uniprot IDs		O60264	Q05DG0 Q96T23
PDB IDs		6NE3
Enriched GO Terms of Interacting Partners?
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