PARD6B and FRMD6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PARD6B	FRMD6
Description		par-6 family cell polarity regulator beta	FERM domain containing 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Plasma Membrane Bicellular Tight Junction Cell Cortex Apical Plasma Membrane Protein-containing Complex Extracellular Exosome	Cytoplasm Cytoskeleton Plasma Membrane
	Molecular Function	Protein Kinase C Binding Protein Binding	Protein Binding
	Biological Process	Cell-cell Junction Assembly Centrosome Cycle Establishment Or Maintenance Of Cell Polarity Axonogenesis Regulation Of Cell Migration Cell Division Regulation Of Cellular Localization Protein-containing Complex Assembly	Actomyosin Structure Organization
Pathways		Tight junction interactions RHOV GTPase cycle
Drugs
Diseases
GWAS		Bipolar disorder ( 21771265)	Anticoagulant levels ( 22216198) Brain structure ( 20171287) Cognitive decline rate in late mild cognitive impairment ( 26252872) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Hippocampal atrophy ( 19668339) Lung cancer (smoking interaction) ( 24658283) Multiple sclerosis ( 31604244) Nonsyndromic cleft lip with or without cleft palate ( 28087736) Total ventricular volume ( 21116278) Triglyceride levels x loop diuretics use interaction ( 31806883)
Interacting Genes		34 interacting genes: APP ARAP3 BANP CDC42 CDCA4 CEP76 FRMD6 GMCL1 GOLGA2 HSF2BP HTRA1 MAGOHB OGT PALS1 PARD3 PARD3B PARD6A PNMA1 PRKCG PRKCI PRKCZ RAC1 RASSF3 RHOJ RHOQ SIAH1 TCP10L3 TRIB3 TRIM35 WDR83 YWHAB YWHAH YWHAZ ZSCAN4	27 interacting genes: - BLZF1 COX6B2 DNAJA3 EXOC5 GMCL1 HMBOX1 IKZF1 JMJD6 LZTS2 MAK16 MED4 MID2 MLH1 NKAPD1 PARD6B RASSF8 SSX2IP SUV39H1 SYT17 TCF12 TLK2 TRIM55 TRIM63 TSC22D4 WDR7 YWHAB
Entrez ID		84612	122786
HPRD ID		18703	12646
Ensembl ID		ENSG00000124171	ENSG00000139926
Uniprot IDs		Q9BYG5	Q96NE9
PDB IDs
Enriched GO Terms of Interacting Partners?
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