RHOXF2 and NANOG

Number of citations of the paper that reports this interaction (PubMedID 20211142)
361

Data Source:
BioGRID (two hybrid)

		RHOXF2	NANOG
Description		Rhox homeobox family member 2	Nanog homeobox
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Chromatin Nucleus Nucleoplasm Nucleolus Intracellular Membrane-bounded Organelle
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Identical Protein Binding Sequence-specific Double-stranded DNA Binding	Transcription Cis-regulatory Region Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Gene Expression	Negative Regulation Of Transcription By RNA Polymerase II Endodermal Cell Fate Specification Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Regulation Of Gene Expression Stem Cell Population Maintenance Cell Differentiation Somatic Stem Cell Population Maintenance Regulation Of Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Stem Cell Proliferation
Pathways			POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation Transcriptional regulation of pluripotent stem cells Interleukin-4 and Interleukin-13 signaling
Drugs
Diseases
GWAS
Interacting Genes		101 interacting genes: ARID5A ARMCX2 ARSA ATN1 ATXN1 BATF3 BOLL C1orf94 CAMK2A CCDC33 CCNK CEACAM6 CERCAM CHAC1 CLASRP CLDN7 CREM CRX CRYBA1 DAB1 DAZAP2 DEDD2 DTX2 DVL2 EFEMP2 EWSR1 FAM166A FAM168A FAM168B FBF1 HNRNPLL HOXC13 HYPK KHDC4 KLHDC7B KRTAP12-2 KRTAP13-2 KRTAP13-4 KRTAP15-1 KRTAP19-5 KRTAP19-6 KRTAP19-7 KRTAP26-1 KRTAP6-1 KRTAP6-2 KRTAP7-1 LASP1 LENG8 LSM4 LZTS2 MAGED1 MDFI MED7 MGAT5B MSX2 MVP NANOG NEU4 NKX1-2 NKX3-1 PITX1 PLAC8 PLOD3 POLR3D POU2AF1 PRR20A PRR20B PRR20C PRR20D PRR20E PRR34 PSMF1 RADIL RAMAC RBFOX1 RBFOX2 RBM11 RBPMS RBPMS2 RNF4 SERF2 SNAPC1 SUMO1 TENT5A TENT5B TENT5C TENT5D TEP1 TLE5 TMCC2 TOLLIP TRIP13 UBAP2 UBE2I UPF1 UTP6 VAC14 VENTX VPS25 ZBTB32 ZNF683	7 interacting genes: BRAF MED12 PRKCE RBPMS RHOXF2 SPOP USP21
Entrez ID		84528	79923
HPRD ID		02345	06397
Ensembl ID		ENSG00000131721	ENSG00000111704
Uniprot IDs		Q9BQY4	A8K4D1 Q9H9S0
PDB IDs			2KT0 4RBO
Enriched GO Terms of Interacting Partners?
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