DCTN5 and KDM8

		DCTN5	KDM8
Description		dynactin subunit 5	lysine demethylase 8
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GO Annotations	Cellular Component	Kinetochore Nucleoplasm Centrosome Cytosol Nuclear Membrane	Nucleus Nucleoplasm Chromosome Cytosol
	Molecular Function	Protein Binding	Chromatin Binding Endopeptidase Activity Aminopeptidase Activity Protein Binding 2-oxoglutarate-dependent Dioxygenase Activity Methylated Histone Binding Metal Ion Binding Histone H3-methyl-lysine-36 Demethylase Activity Peptidyl-arginine 3-dioxygenase Activity
	Biological Process	Ventricular Septum Development Aorta Development Coronary Vasculature Development	G2/M Transition Of Mitotic Cell Cycle Proteolysis Protein Destabilization Circadian Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Histone H3-K36 Demethylation
Pathways		MHC class II antigen presentation HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand COPI-mediated anterograde transport COPI-independent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS		Bipolar disorder ( 17554300)	Asthma ( 31959851 31619474) Gut microbiota (bacterial taxa) ( 27723756) Night sleep phenotypes ( 27126917)
Interacting Genes		10 interacting genes: C16orf82 CHP2 COG7 DYNLL1 EARS2 FATE1 KDM8 NINL PMEPA1 RBPMS	8 interacting genes: DCTN5 DDIT4L H3C1 IFT20 ISY1 MEOX2 NUBPL PCYT2
Entrez ID		84516	79831
HPRD ID		14551	07836
Ensembl ID		ENSG00000166847	ENSG00000155666
Uniprot IDs		Q9BTE1	A0A0S2Z5P8 A0A0S2Z5T1 Q8N371
PDB IDs		5NW4	3UYJ 4AAP 4GAZ 4GJY 4GJZ 4QU1 5FBJ 6AVS 6AX3 6F4M 6F4N 6F4O 6F4P 6F4Q 6F4R 6F4S 6F4T 6I9L 6I9M 6I9N
Enriched GO Terms of Interacting Partners?
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