HOOK3 and CTIF

Number of citations of the paper that reports this interaction (PubMedID 29395067)
145

Data Source:
BioGRID (two hybrid, proximity labelling technology)

		HOOK3	CTIF
Description		hook microtubule tethering protein 3	cap binding complex dependent translation initiation factor
Image			No pdb structure
GO Annotations	Cellular Component	Pericentriolar Material Cytoplasm Cis-Golgi Network Centrosome Cytosol Microtubule Centriolar Satellite FHF Complex	Cytosol Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Microtubule Binding Dynactin Binding Identical Protein Binding Dynein Light Chain Binding Dynein Intermediate Chain Binding Dynein Light Intermediate Chain Binding	RNA Binding Protein Binding Translation Activator Activity
	Biological Process	Endosome Organization Lysosome Organization Endosome To Lysosome Transport Protein Transport Interkinetic Nuclear Migration Cytoskeleton-dependent Intracellular Transport Cytoplasmic Microtubule Organization Microtubule Anchoring At Centrosome Early Endosome To Late Endosome Transport Negative Regulation Of Neurogenesis Golgi Localization Protein Localization To Centrosome Neuronal Stem Cell Population Maintenance Protein Localization To Perinuclear Region Of Cytoplasm	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Regulation Of Translational Initiation Positive Regulation Of Translation
Pathways
Drugs
Diseases
GWAS		Zinc levels ( 26025379)	Automobile speeding propensity ( 30643258) Ceramide levels (C22:0) ( 32489964) Ceramide levels (C24:0) ( 32489964) Height ( 31562340) Hematocrit ( 32888494) Hemoglobin ( 32888494) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Iris heterochromicity ( 30895295) Large HDL particle concentration ( 29084231) Lumbar spine bone mineral density (integral) ( 27476799) Mean diameter of HDL particles ( 29084231) Phospholipid levels in large HDL ( 29084231) Red blood cell count ( 32888494 27863252) Response to carboplatin in ovarian cancer (MTT IC50) ( 27047539) Rheumatoid arthritis ( 30891314) White blood cell count ( 32888494)
Interacting Genes		13 interacting genes: AKTIP CTIF HOOK1 HOOK2 IDO2 KRT13 KRT27 MAPT MEOX2 MORC3 PNMA5 VPS16 VPS41	9 interacting genes: ATPAF2 ATXN7L2 DDX19A HEXIM2 HOOK3 MIF4GD RECK SPG21 TCF4
Entrez ID		84376	9811
HPRD ID		09699	11083
Ensembl ID		ENSG00000168172	ENSG00000134030
Uniprot IDs		Q86VS8	A0A024R259 O43310
PDB IDs		5J8E 6B9H
Enriched GO Terms of Interacting Partners?
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