TMEM107 and THAP4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TMEM107	THAP4
Description		transmembrane protein 107	THAP domain containing 4
Image		No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane Ciliary Transition Zone MKS Complex	Cellular_component
	Molecular Function	Molecular_function Protein Binding	DNA Binding Protein Binding Heme Binding Identical Protein Binding Metal Ion Binding Peroxynitrite Isomerase Activity Nitric Oxide Binding
	Biological Process	Detection Of Nodal Flow Regulation Of Gene Expression Neural Tube Patterning Embryonic Digit Morphogenesis Roof Of Mouth Development Cilium Assembly Craniofacial Suture Morphogenesis Protein Localization To Ciliary Transition Zone Non-motile Cilium Assembly	Tyrosine Metabolic Process Nitrate Metabolic Process
Pathways
Drugs
Diseases
GWAS		Diastolic blood pressure ( 30224653) Urinary potassium excretion ( 31409800)	Brain structure ( 20171287) Hip circumference adjusted for BMI ( 34021172) Platelet count ( 32888494) Prostate cancer ( 23535732) Thyroid stimulating hormone levels ( 32769997)
Interacting Genes		44 interacting genes: AQP3 AQP6 BIK CCL21 CD40 CD79A CLN8 CLSTN3 EBAG9 ERGIC3 EVI2B FAM209A FAM210B FCER1G GJA5 GJA8 GPX8 KCNA5 KCNJ6 LHFPL5 LMNA MGST3 MS4A3 PDZK1IP1 PGRMC2 PIGP SAR1A SLC10A6 SLC30A2 SLC35C2 SLC39A2 SYT2 THAP4 TMEM106A TMEM139 TMEM167B TMEM234 TMEM237 TMEM31 TMEM51 TMEM52B TMEM80 TMEM86B VMA21	42 interacting genes: AGTRAP AIG1 AMD1 ANKRD46 APP BSND CACNG1 CD81 CLCA4 CMTM5 CMTM7 COL4A5 CPNE2 CTSA CYP4F2 DGAT2L6 FKBP7 GIMAP1 GPR37L1 IGFBP5 LAT LPAR3 MAL2 MAPK6 MOB4 MS4A1 NDRG4 PLP2 RMDN2 RTP2 SCAMP1 SLC30A8 SYP TMEM107 TMEM60 TMEM86A TMEM86B TNFRSF10D TPD52 TRIM54 TTPA YIPF6
Entrez ID		84314	51078
HPRD ID		14400	11630
Ensembl ID		ENSG00000179029	ENSG00000176946
Uniprot IDs		Q6UX40	Q8WY91
PDB IDs			3IA8
Enriched GO Terms of Interacting Partners?
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