CASP9 and APAF1

  • Number of citations of the paper that reports this interaction (PubMedID 9390557)
  • 1407
  • Data Source:
  • HPRD (in vitro, in vivo)

CASP9

APAF1

Description caspase 9 apoptotic peptidase activating factor 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alcoholic chronic pancreatitis ( 28754779)
  • Estimated glomerular filtration rate ( 30604766)
  • Glomerular filtration rate (creatinine) ( 28452372 26831199)
  • Glomerular filtration rate in non diabetics (creatinine) ( 26831199)
  • Orofacial cleft x maternal periconceptional multivitamin use interaction (1df) ( 33937227)
  • Orofacial cleft x maternal periconceptional multivitamin use interaction (2df) ( 33937227)
  • Serum metabolite levels ( 33031748)
  • Urate levels ( 31578528)
  • Urinary metabolite levels in chronic kidney disease ( 31959995)
Interacting Genes 48 interacting genes: ABL1 AKT1 APAF1 ARNT BCL10 BCL2L1 BIRC2 BIRC3 BIRC5 BIRC6 BIRC7 BIRC8 CAPN2 CARD8 CASP10 CASP12 CASP3 CASP7 CASP8 CYCS DCC DIABLO DSP GMEB1 GZMB HECTD3 HIP1 HSD17B4 HSPD1 ILK JUN LYN MAP2K1 MAP2K2 MAPK1 MAPK3 MSTO1 MZB1 NAIP NLRP1 NOD1 PRKCZ RB1 RNF2 SLIT3 SRF VIM XIAP 30 interacting genes: ACADS APIP AVEN BCL2L1 BCL2L10 CASP3 CASP4 CASP8 CASP9 CCL13 CDK17 CYCS DZIP1 ELK3 FAS FEM1B HIP1 HNF1A HSP90AA1 HSPA1A MRPL19 NLRP1 NR1H4 NUDT4 PAH PPP1CA RPL26L1 TOP1 TRIAP1 UTP20
Entrez ID 842 317
HPRD ID 03756 03755
Ensembl ID ENSG00000132906 ENSG00000120868
Uniprot IDs F8VVS7 P55211 O14727
PDB IDs 1JXQ 1NW9 2AR9 3D9T 3V3K 3YGS 4RHW 5JUY 5WVC 5WVE 1C15 1CWW 1CY5 1Z6T 2P1H 2YGS 3J2T 3JBT 3YGS 4RHW 5JUY 5WVC 5WVE
Enriched GO Terms of Interacting Partners?
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