ZNRF3 and RSPO3

  • Number of citations of the paper that reports this interaction (PubMedID 29752411)
  • 20
  • Data Source:
  • BioGRID (fluorescent resonance energy transfer, pull down, pull down)

ZNRF3

RSPO3

Description zinc and ring finger 3 R-spondin 3
Image No pdb structure No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alanine aminotransferase levels ( 34315874)
  • Apolipoprotein A1 levels ( 32203549)
  • Apolipoprotein B levels ( 32203549)
  • Aspartate aminotransferase levels ( 33547301 34315874)
  • Blood pressure ( 23972371)
  • Blood protein levels ( 30072576 29875488)
  • Blood urea nitrogen levels ( 31152163 29403010)
  • Body shape index ( 34021172)
  • Bone mineral density ( 21533022)
  • Bone mineral density (paediatric, skull) ( 24945404)
  • Bone mineral density (paediatric, total body less head) ( 24945404)
  • Bone mineral density (paediatric, upper limb) ( 24945404)
  • Bone mineral density (spine) ( 26733130)
  • Bone properties (heel) ( 24430505)
  • Bone ultrasound measurement (broadband ultrasound attenuation) ( 28472463)
  • Bone ultrasound measurement (velocity of sound) ( 28472463)
  • C-reactive protein levels or HDL-cholesterol levels (pleiotropy) ( 27286809)
  • Cleft lip with or without cleft palate x maternal periconceptional vitamin use interaction (parent of origin effect) ( 31372216)
  • Cortical surface area ( 32963231)
  • Cortical volume ( 32963231)
  • Crohn's disease ( 28067908)
  • Diastolic blood pressure ( 27841878 29403010 28739976 27618452 30487518)
  • Diastolic blood pressure (cigarette smoking interaction) ( 29455858)
  • Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
  • Fasting insulin ( 33402679 34059833)
  • Femoral neck bone mineral density ( 29499414 22504420)
  • Food addiction ( 27106561)
  • Fractures ( 30158200 30598549)
  • HDL cholesterol ( 24097068 30275531)
  • HDL cholesterol levels ( 32203549 28334899 30698716)
  • HDL cholesterol levels in current drinkers ( 30698716)
  • HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • HDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535)
  • HDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535)
  • Heel bone mineral density ( 30598549 30048462 28869591)
  • Hematocrit ( 32888494)
  • Hemoglobin ( 32888494)
  • Hemoglobin concentration ( 27863252)
  • Hemoglobin levels ( 32327693)
  • High density lipoprotein cholesterol levels ( 33339817)
  • Hip circumference ( 31453325)
  • Hip circumference adjusted for BMI ( 34021172 25673412)
  • Hip circumference variance ( 31453325)
  • Hip index ( 34021172)
  • Intracranial volume ( 22504418)
  • Iron status biomarkers ( 19084217)
  • LDL cholesterol levels ( 32203549)
  • LDL cholesterol levels in HIV infection ( 33109212)
  • Liver enzyme levels (gamma-glutamyl transferase) ( 33972514)
  • Liver transplant-free survival in primary sclerosing cholangitis (time to event) ( 28779025)
  • Liver volume ( 34128465)
  • Low density lipoprotein cholesterol levels ( 32154731)
  • Lung function (FVC) ( 30061609)
  • Lymphocyte counts ( 32888494)
  • Lymphocyte percentage of white cells ( 32888494)
  • Male-pattern baldness ( 27182965)
  • Mean arterial pressure ( 29403010 30487518)
  • Mean arterial pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Medication use (HMG CoA reductase inhibitors) ( 31015401)
  • Menarche (age at onset) ( 27182965)
  • Metabolic syndrome ( 31589552)
  • Metabolite levels ( 21909109)
  • Monobrow ( 27182965)
  • Neutrophil percentage of white cells ( 32888494)
  • Occipital lobe volume ( 31396565)
  • Optic disc size ( 31809533)
  • Pancreas volume ( 34128465)
  • Pulse pressure ( 27841878)
  • QT interval ( 29213071)
  • Red blood cell count ( 32888494 27863252)
  • Renal function-related traits (BUN) ( 22797727)
  • Serum urea levels ( 30808845)
  • Subcortical brain region volumes ( 25607358)
  • Systolic blood pressure ( 27841878 28739976 27618452 30487518)
  • Systolic blood pressure (cigarette smoking interaction) ( 29455858)
  • Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Triglyceride levels ( 32203549 28334899 32154731)
  • Triglyceride levels in current drinkers ( 30698716)
  • Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Triglycerides ( 24097068 25961943)
  • Waist circumference ( 25673412)
  • Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
  • Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500)
  • Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
  • Waist circumference adjusted for BMI in active individuals ( 28448500)
  • Waist circumference adjusted for BMI in non-smokers ( 28443625)
  • Waist circumference adjusted for body mass index ( 28552196 34021172 25673412 28448500)
  • Waist-hip index ( 34021172)
  • Waist-hip ratio ( 28552196 23563607 25673412 20935629)
  • Waist-to-hip ratio adjusted for BMI ( 28552196 34021172 26426971)
  • Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)
  • Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
  • Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971)
  • Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500)
  • Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
  • Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500)
  • Waist-to-hip ratio adjusted for BMI in non-smokers ( 28443625)
  • Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
  • Waist-to-hip ratio adjusted for body mass index ( 28270201 25673412 28448500)
Interacting Genes 8 interacting genes: C3orf52 GFI1B HOXA1 HSPB1 RSPO1 RSPO2 RSPO3 UBE2N 4 interacting genes: HRAS LGR4 MTDH ZNRF3
Entrez ID 84133 84870
HPRD ID 11737 18181
Ensembl ID ENSG00000183579 ENSG00000146374
Uniprot IDs A0A024R1J1 Q9ULT6 Q9BXY4
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?