EEA1 and RRAD

Number of citations of the paper that reports this interaction (PubMedID 25313011)
14

Data Source:
BioGRID (pull down)

		EEA1	RRAD
Description		early endosome antigen 1	RRAD, Ras related glycolysis inhibitor and calcium channel regulator
Image
GO Annotations	Cellular Component	Cytoplasm Early Endosome Cytosol Serine-pyruvate Aminotransferase Complex Membrane Extrinsic Component Of Plasma Membrane Early Endosome Membrane Axonal Spine Recycling Endosome Extracellular Exosome	Cytosol Plasma Membrane
	Molecular Function	Protein Binding Calmodulin Binding 1-phosphatidylinositol Binding Zinc Ion Binding GTP-dependent Protein Binding Protein Homodimerization Activity	GTPase Activity Calcium Channel Regulator Activity Protein Binding Calmodulin Binding GTP Binding
	Biological Process	Endocytosis Vesicle Fusion Synaptic Vesicle To Endosome Fusion Viral RNA Genome Replication Early Endosome To Late Endosome Transport	Small GTPase Mediated Signal Transduction Negative Regulation Of High Voltage-gated Calcium Channel Activity
Pathways		Toll Like Receptor 9 (TLR9) Cascade	NGF-stimulated transcription
Drugs		Inositol 1,3-Bisphosphate
Diseases
GWAS		Diastolic blood pressure x smoking status (current vs non-current) interaction (1df test) ( 29455858) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Sensorimotor dexterity ( 31596458) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Western dietary pattern ( 28644415)	Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		13 interacting genes: IGF1R MAPK14 RAB22A RAB31 RAB5A RAB5B RAB5C RRAD STX12 STX6 TOM1 USO1 ZFYVE16	15 interacting genes: CALM1 CAMK2G CCDC141 CSNK2A1 CSNK2B EEA1 EGFR MMP14 NME1 PRKACA PRKCA PRKCB STAT3 TPM2 YWHAZ
Entrez ID		8411	6236
HPRD ID		05460	01536
Ensembl ID		ENSG00000102189	ENSG00000166592
Uniprot IDs		Q15075	A0A024R6X0 P55042
PDB IDs		1HYI 1HYJ 1JOC 3MJH	2DPX 2GJS 3Q72 3Q7P 3Q7Q
Enriched GO Terms of Interacting Partners?
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