PCGF6 and CBX7

Number of citations of the paper that reports this interaction (PubMedID 26186194)
524

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down)

		PCGF6	CBX7
Description		polycomb group ring finger 6	chromobox 7
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm PcG Protein Complex PRC1 Complex	Chromatin Nucleus Nucleoplasm Cytosol PcG Protein Complex PRC1 Complex
	Molecular Function	Protein Binding Metal Ion Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Histone H2A-K119 Monoubiquitination Negative Regulation Of Transcription, DNA-templated	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization
Pathways		Transcriptional Regulation by E2F6
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Response to cognitive-behavioural therapy in major depressive disorder ( 31123309) Schizophrenia ( 25056061 29483656 23974872)	Hematocrit ( 32888494) Hemoglobin ( 32888494) Immunoglobulin light chain (AL) amyloidosis ( 28025584) Lymphocyte counts ( 32888494 27863252) Menarche (age at onset) ( 25231870) Multiple myeloma ( 26007630 23955597) Multiple myeloma and monoclonal gammopathy ( 26007630) Neutrophil count ( 32888494) White blood cell count ( 32888494 27863252)
Interacting Genes		27 interacting genes: BMI1 CBX6 CBX7 CDK7 E2F6 EIF2B2 H3-4 KDM5D MAGEA1 MAGEC2 MAGEE2 MAGEL2 OGT PEX10 PNMA1 RAD18 RING1 RNF2 SS18L1 TRIM14 TRIM55 TRIM63 TULP3 UBE2D3 UBE2U USP2 USP21	8 interacting genes: B3GNT5 H3-4 PCGF1 PCGF5 PCGF6 RING1 SUV39H2 ZRANB1
Entrez ID		84108	23492
HPRD ID		07427	12234
Ensembl ID		ENSG00000156374	ENSG00000100307
Uniprot IDs		Q9BYE7	A0A024R1Q2 B0QYP2 O95931 Q4PNR6
PDB IDs		2DJB	2K1B 2L12 2L1B 3GS2 4MN3 5EPJ 6V2R
Enriched GO Terms of Interacting Partners?
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