DTNBP1 and TPMT

DTNBP1

TPMT

Description dystrobrevin binding protein 1 thiopurine S-methyltransferase
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Asthma exacerbations in inhaled corticosteroid treatment ( 30697902)
  • Corneal astigmatism ( 30306274)
  • Liver enzyme levels (alkaline phosphatase) ( 33972514)
  • Multiple myeloma ( 27363682)
  • Serum alkaline phosphatase levels ( 33547301)
  • Squamous cell carcinoma ( 31174203)
  • DNA-incorporated thioguanine levels in 6-mercaptopurine-treated acute lymphoblastic leukaemia ( 30201983)
  • Erythrocyte methylated 6-mercaptopurine metabolite concentration in 6-mercaptopurine-treated acute lymphoblastic leukaemia ( 30201983)
  • Erythrocyte thioguanine concentration in 6-mercaptopurine-treated acute lymphoblastic leukaemia ( 30201983)
  • Thiopurine methyltransferase activity in acute lymphoblastic leukemia patients treated with mercaptopurines ( 27564568)
  • Thiopurine S-methyltransferase activity ( 27770449)
  • Thiopurine-induced myelosuppression in inflammatory bowel disease ( 30806694)
Interacting Genes 58 interacting genes: ABI3 AKAP6 ARFIP2 BICRAL BLOC1S3 BLOC1S5 BLOC1S6 BRF1 CAP2 CCDC146 CCDC153 CCNA2 CCND3 CMYA5 CSGALNACT1 DCTN1 DEK DGCR6L DST DTNA DTNB ELOVL7 HAUS1 HDGFL1 IFT20 IPO5 KALRN KANSL1 KIAA0408 KIFC3 KRT75 MACF1 NBEA NDN NECAB2 NUF2 NUP153 OIP5 P4HA3 PSME3 RAB11A RBSN RNF144B SDCBP SFR1 SHFL SNAPIN SRGAP3 SSC5D SYNE1 TPMT TRAF3IP1 TRIM2 TRIM27 TRIM9 VRK2 WASHC3 ZNF490 3 interacting genes: APP DTNBP1 FGFR1
Entrez ID 84062 7172
HPRD ID 06190 01760
Ensembl ID ENSG00000047579 ENSG00000137364
Uniprot IDs A0A087WYP9 A0A0S2Z5U8 A6NFV8 D6RJC6 Q96EV8 A0A024QZW0 P51580
PDB IDs 2BZG 2H11
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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