GPR61 and GJB6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		GPR61	GJB6
Description		G protein-coupled receptor 61	gap junction protein beta 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endosome Plasma Membrane Endosome Membrane Integral Component Of Membrane Receptor Complex	Cytosol Actin Filament Gap Junction Connexin Complex Integral Component Of Membrane Apical Plasma Membrane Cell Junction
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding Arrestin Family Protein Binding	Gap Junction Channel Activity Protein Binding Microtubule Binding Beta-tubulin Binding Actin Filament Binding Gap Junction Channel Activity Involved In Cell Communication By Electrical Coupling
	Biological Process	G Protein-coupled Receptor Signaling Pathway Positive Regulation Of CAMP-mediated Signaling	Sinoatrial Node Development Apoptotic Process Cell-cell Signaling Aging Sensory Perception Of Sound Negative Regulation Of Cell Population Proliferation Cell Communication By Electrical Coupling Gap Junction Assembly Response To Lipopolysaccharide Maintenance Of Blood-brain Barrier Ear Morphogenesis Inner Ear Development Response To Electrical Stimulus Transmembrane Transport Cellular Response To Glucose Stimulus Gap Junction-mediated Intercellular Transport
Pathways			Gap junction assembly
Drugs
Diseases
GWAS		Adult body size ( 32376654) Body mass index ( 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index in physically active individuals ( 28448500) Body size at age 10 ( 32376654) Childhood body mass index ( 26604143) Chronotype ( 30696823) Hepcidin/ferritin ratio ( 27846281) Morning person ( 30696823) Schizophrenia, bipolar disorder or major depressive disorder x sex interaction (3df) ( 34099189) Stearic acid (18:0) levels ( 23362303) Waist circumference ( 25673412)	Facial emotion recognition (happy faces) ( 28608620) Triglyceride levels x fish oil supplementation interaction (1df) ( 33760818)
Interacting Genes		20 interacting genes: APP ARL6IP6 ATP6V0B C4orf3 CLDND1 CTXN3 EMP3 FCER1G GJA8 GJB6 KLRC1 PLP1 PMP22 SCN3B SLC12A7 SLC13A4 STRIT1 TMEM147 TMEM218 TRARG1	14 interacting genes: CHRM5 CNST EBP F2RL1 GJB2 GPR61 KLRC1 LHFPL5 MS4A13 SEC22A SEC22B SLC10A6 TMEM218 TMEM60
Entrez ID		83873	10804
HPRD ID		06077	05107
Ensembl ID		ENSG00000156097	ENSG00000121742
Uniprot IDs		G4XH66 Q9BZJ8	A0A024RDS4 O95452
PDB IDs
Enriched GO Terms of Interacting Partners?
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