APH1B and NCSTN

  • Number of citations of the paper that reports this interaction (PubMedID 12857757)
  • 74
  • Data Source:
  • HPRD (in vitro, in vivo)

APH1B

NCSTN

Description aph-1 homolog B, gamma-secretase subunit nicastrin
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alzheimer's disease or family history of Alzheimer's disease ( 30617256)
  • Estimated glomerular filtration rate ( 31152163)
  • Family history of Alzheimer's disease ( 30617256)
  • Metabolite levels ( 23823483)
  • Myopia ( 27182965)
  • Refractive error ( 32231278)
  • Response to fenofibrate (triglyceride levels) ( 27002377)
  • Spherical equivalent or myopia (age of diagnosis) ( 29808027)
  • Post bronchodilator FEV1 in COPD ( 26634245)
Interacting Genes 8 interacting genes: FXYD6-FXYD2 NAB2 NCSTN PSEN1 PSEN2 TM4SF4 TRARG1 VSTM1 12 interacting genes: ABL1 APH1A APH1B APP BACE1 MAPK9 PSEN1 PSEN2 PSENEN PTEN SPP1 TMED10
Entrez ID 83464 23385
HPRD ID 06361 05584
Ensembl ID ENSG00000138613 ENSG00000162736
Uniprot IDs Q8WW43 B4DR82 Q92542
PDB IDs 2N7Q 2N7R 4UIS 5A63 5FN2 5FN3 5FN4 5FN5 6IDF 6IYC 6LQG 6LR4 7C9I 7D8X
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?