SYN3 and SYN2

Number of citations of the paper that reports this interaction (PubMedID 10358015)
31

Data Source:
HPRD (in vivo, in vitro, two hybrid)

		SYN3	SYN2
Description		synapsin III	synapsin II
Image			No pdb structure
GO Annotations	Cellular Component	Synaptic Vesicle Postsynaptic Density Synaptic Vesicle Membrane Glutamatergic Synapse	Plasma Membrane Postsynaptic Density Synaptic Vesicle Membrane SNARE Complex Synapse Schaffer Collateral - CA1 Synapse Glutamatergic Synapse
	Molecular Function	ATP Binding	ATP Binding Identical Protein Binding
	Biological Process	Neurotransmitter Secretion Regulation Of Synaptic Transmission, GABAergic Synaptic Vesicle Clustering	Chemical Synaptic Transmission Neurotransmitter Secretion Calcium-ion Regulated Exocytosis Synaptic Vesicle Clustering
Pathways		Serotonin Neurotransmitter Release Cycle Dopamine Neurotransmitter Release Cycle	Serotonin Neurotransmitter Release Cycle Dopamine Neurotransmitter Release Cycle
Drugs
Diseases
GWAS		Advanced age-related macular degeneration ( 26691988) Age-related macular degeneration ( 20385819) Alzheimer's disease progression score ( 29860282) Benign prostatic hyperplasia ( 30988330) Blood protein levels ( 29875488 28240269) Chronic obstructive pulmonary disease ( 30804561) Femoral neck bone mineral density and trunk fat mass adjusted by trunk lean mass ( 32239398) Heel bone mineral density ( 30598549) Height ( 21998595 20881960 25282103 25429064 31562340) Interleukin-6 levels ( 22205395) Intracranial aneurysm ( 29531279) Intraocular pressure ( 29617998 29785010 31959993 30054594) Metabolite levels ( 23823483) Refractive error ( 32231278) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Triglyceride levels ( 31170924) Trunk fat mass adjusted for trunk lean mass ( 32239398)	Body shape index ( 34021172) Chronic obstructive pulmonary disease ( 30804561) Circulating leptin levels or type 2 diabetes ( 32341051) Creatinine levels ( 29403010) Eosinophil counts ( 32888494) Estimated glomerular filtration rate ( 31152163) Fasting blood insulin (BMI interaction) ( 22581228) Glomerular filtration rate ( 29403010) Glycated hemoglobin levels ( 34059833 28898252) Heel bone mineral density ( 30598549) Height ( 28552196) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) LDL cholesterol levels ( 30698716) LDL cholesterol levels in current drinkers ( 30698716) LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Leprosy ( 27976721) Nontraumatic osteonecrosis of the femoral head ( 32701715) Platelet count ( 22139419 29403010) Thyroid stimulating hormone levels ( 32769997 25743335) Triglycerides ( 30275531) Type 2 diabetes ( 18372903) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		7 interacting genes: C9orf72 MORF4L1 MORF4L2 NOS1AP PIAS2 SYN1 SYN2	7 interacting genes: CHRM4 NOS1AP PRKACA SYN1 SYN3 YWHAE YWHAZ
Entrez ID		8224	6854
HPRD ID		04083	02857
Ensembl ID		ENSG00000185666	ENSG00000157152
Uniprot IDs		A0A024R1I8 O14994 Q17R54 Q59EX7	B3KRB3 Q59GM1 Q86VA8 Q92777
PDB IDs		2P0A
Enriched GO Terms of Interacting Partners?
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