MED25 and SERTAD3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		MED25	SERTAD3
Description		mediator complex subunit 25	SERTA domain containing 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Transcription Regulator Complex Mediator Complex	Nucleus
	Molecular Function	Transcription Coactivator Binding Protein Binding Transcription Factor Binding Retinoic Acid Receptor Binding Retinoid X Receptor Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Chromatin Binding Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Fibroblast Proliferation Regulation Of Cell Cycle Positive Regulation Of Mediator Complex Assembly	Regulation Of Transcription, DNA-templated Negative Regulation Of Cell Growth Positive Regulation Of Transcription, DNA-templated
Pathways		PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases
GWAS		Blood trace element (Se levels) ( 23720494)	Mean reticulocyte volume ( 32888494) Otitis media ( 27632927) Otitis media (chronic) ( 27632927) Otitis media (recurrent) ( 27632927)
Interacting Genes		37 interacting genes: CDK8 CREBBP CTDP1 CYSRT1 ESRP1 EYA2 FAM168B HCFC1 HGS KLHL12 KRTAP6-1 KRTAP6-3 LASP1 MED1 MED15 MED6 MED8 MED9 NCKIPSD NR3C1 ODAM OXER1 PEF1 PLEKHB2 RARA RORB RUSC1 RXRA SERTAD3 SREBF1 STAT5B TFG THRA TLE5 USP54 WWOX WWP2	44 interacting genes: ANKRD11 BEX2 BFSP2 C1orf216 CCNC CENPP CREBBP CTNNAL1 DPPA3 FAAP20 FBXO44 FCHSD2 GTPBP3 HGS IL16 IMP3 KANK2 KLHL42 KPNA2 MBD3 MED25 MSGN1 NDN NPPB P4HA3 PICK1 PKN1 PRKAA2 RPA2 RTP5 SMARCD1 SNRPB SPG11 SUOX TASOR2 TBCE TLE5 TNPO2 TPRX1 TRAPPC6A TXN UBL5 USHBP1 ZGPAT
Entrez ID		81857	29946
HPRD ID		14380	15327
Ensembl ID		ENSG00000104973	ENSG00000167565
Uniprot IDs		Q71SY5	A0A024R0N2 Q9UJW9
PDB IDs		2KY6 2L23 2L6U 2XNF
Enriched GO Terms of Interacting Partners?
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