MAP1LC3B and TBC1D17

Number of citations of the paper that reports this interaction (PubMedID 22354992)
83

Data Source:
BioGRID (two hybrid)

		MAP1LC3B	TBC1D17
Description		microtubule associated protein 1 light chain 3 beta	TBC1 domain family member 17
Image			No pdb structure
GO Annotations	Cellular Component	Autophagosome Membrane Mitochondrion Autophagosome Cytosol Microtubule Axoneme Endomembrane System Organelle Membrane Cytoplasmic Vesicle Intracellular Membrane-bounded Organelle	Autophagosome Cytosol Recycling Endosome
	Molecular Function	Protein Binding Microtubule Binding Ubiquitin Protein Ligase Binding Ceramide Binding	GTPase Activator Activity Protein Binding
	Biological Process	Autophagosome Assembly Autophagy Of Mitochondrion Mitophagy Autophagy Cellular Response To Nitrogen Starvation Cellular Response To Starvation Macroautophagy Autophagosome Maturation	Intracellular Protein Transport Autophagy Retrograde Transport, Endosome To Golgi Activation Of GTPase Activity Regulation Of Cilium Assembly
Pathways		Macroautophagy PINK1-PRKN Mediated Mitophagy TBC/RABGAPs Receptor Mediated Mitophagy Pexophagy Translation of Replicase and Assembly of the Replication Transcription Complex Translation of Replicase and Assembly of the Replication Transcription Complex	TBC/RABGAPs
Drugs
Diseases
GWAS		General factor of neuroticism ( 30867560) Major depressive disorder ( 22472876) Metabolite levels ( 23823483) Neuroticism ( 29255261) Refractive error ( 32231278)
Interacting Genes		73 interacting genes: AAMP ADD1 ADNP AMBRA1 ANK2 ARFGAP1 ATG13 ATG3 ATG4A ATG4B ATG4C ATG4D ATG7 BAG6 BIRC6 BNIP3 BRD3 CASP8 CCDC50 CCSER2 CLTA CUL3 DBI DBN1 DNMT3B EED EPS8 EVA1A FLCN FUNDC1 GABARAPL2 GORASP2 IRGQ KBTBD7 KLHL5 KXD1 LUC7L2 MESD MKRN1 MRFAP1 MYBL2 NEDD4 NEK9 OPTN PRKCZ RAD1 RAP1GAP RETREG2 RIPOR1 RPLP1 SEM1 SMARCB1 SNU13 SNX18 SPAG9 SQSTM1 STK3 STK4 TAF7 TAX1BP1 TBC1D17 TBC1D25 TBC1D9 TBC1D9B TBK1 THAP7 TMOD3 TNIP1 TRIM21 TRIM32 UPF2 USP10 VHL	19 interacting genes: ASCC2 CALCOCO1 CCT5 CDKN2D DHX29 FBL GABARAPL1 GPS1 GTF3C1 MAP1LC3A MAP1LC3B NIPSNAP1 OPTN RAB1A RAB5A RAB5B RAB5C SLC1A5 TAX1BP1
Entrez ID		81631	79735
HPRD ID		14358	15471
Ensembl ID		ENSG00000140941	ENSG00000104946
Uniprot IDs		Q658J6 Q9GZQ8	Q9HA65
PDB IDs		1V49 2LUE 2N9X 2ZJD 3VTU 3VTV 3VTW 3WAO 3X0W 4WAA 5D94 5DCN 5GMV 5MS2 5MS5 5MS6 5V4K 5W9A 5XAC 5XAD 5XAE 6J04 6LAN
Enriched GO Terms of Interacting Partners?
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