TXNDC5 and GMPPB

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		TXNDC5	GMPPB
Description		thioredoxin domain containing 5	GDP-mannose pyrophosphorylase B
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Endoplasmic Reticulum Endoplasmic Reticulum Lumen Azurophil Granule Lumen Lysosomal Lumen Extracellular Exosome	Cytoplasm
	Molecular Function	Protein Disulfide Isomerase Activity Protein Binding	Mannose-1-phosphate Guanylyltransferase Activity Protein Binding GTP Binding Nucleotidyltransferase Activity
	Biological Process	Negative Regulation Of Apoptotic Process Apoptotic Cell Clearance	Cell Wall Mannoprotein Biosynthetic Process Protein Glycosylation GDP-mannose Biosynthetic Process
Pathways		Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis Neutrophil degranulation	Synthesis of GDP-mannose
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488) High chromosomal aberration frequency (chromatid type) ( 31586183) Mean corpuscular hemoglobin ( 32888494) Pelvic organ prolapse ( 32184442)	Blood protein levels ( 28240269) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Extremely high intelligence ( 29520040) Multisite chronic pain ( 31194737) Regular attendance at a gym or sports club ( 29970889) Regular attendance at a religious group ( 29970889) Resting heart rate ( 27798624) Sleep duration (short sleep) ( 30846698) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 21297633)
Interacting Genes		28 interacting genes: APP AR BLZF1 EDEM3 EFEMP1 FLACC1 GMPPB KRT38 KRT40 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP4-12 KRTAP4-2 LHX4 MGAT5B NOTCH2NLA OGT PJA1 PRDX2 RAB3IP SPRY2 TRIM23 TRIM42 TRIP6 UBQLN2	6 interacting genes: DPPA4 GLYCTK GMPPA POLR1C SETD2 TXNDC5
Entrez ID		81567	29925
HPRD ID		18249	13589
Ensembl ID		ENSG00000239264	ENSG00000173540
Uniprot IDs		A0A024QZV0 Q8NBS9	Q9Y5P6
PDB IDs		2DIZ 3UJ1 3UVT 3WGD 3WGE 3WGX
Enriched GO Terms of Interacting Partners?
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