COLEC12 and EXOC1

Number of citations of the paper that reports this interaction (PubMedID 17043677)
193

Data Source:
BioGRID (two hybrid)

		COLEC12	EXOC1
Description		collectin subfamily member 12	exocyst complex component 1
Image			No pdb structure
GO Annotations	Cellular Component	Collagen Trimer Extracellular Space Plasma Membrane Integral Component Of Membrane Endocytic Vesicle Membrane Extracellular Matrix	Exocyst Cytoplasm Cytosol Plasma Membrane Membrane Perinuclear Region Of Cytoplasm Flemming Body Cytoplasmic Side Of Apical Plasma Membrane
	Molecular Function	Scavenger Receptor Activity Galactose Binding Low-density Lipoprotein Particle Binding Pattern Recognition Receptor Activity Metal Ion Binding	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding
	Biological Process	Phagocytosis, Recognition Defense Response Carbohydrate Mediated Signaling Toll-like Receptor 3 Signaling Pathway Defense Response To Bacterium Innate Immune Response Positive Regulation Of Cell Adhesion Molecule Production Cellular Response To Exogenous DsRNA	Exocytosis Golgi To Plasma Membrane Transport Protein Transport Regulation Of Macroautophagy Phosphatidylinositol-mediated Signaling Positive Regulation Of Protein Secretion Defense Response To Virus
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Scavenging by Class A Receptors	Translocation of SLC2A4 (GLUT4) to the plasma membrane Insulin processing VxPx cargo-targeting to cilium
Drugs
Diseases
GWAS		Bipolar disorder ( 20351715) Bipolar disorder or major depressive disorder ( 20351715) Blood protein levels ( 30072576 29875488) Coenzyme Q10 levels ( 27149984) Metabolic syndrome ( 29212154) Obesity-related traits ( 23251661) Schizophrenia x sex interaction ( 34099189) Smoking status (ever vs never smokers) ( 30643258)	Cerebrospinal P-tau181p levels ( 28247064) Cervical cancer ( 23817570) Daytime sleep phenotypes ( 27126917) Urinary albumin excretion ( 32277301) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		6 interacting genes: APP EXOC1 EXOSC2 FBXO7 PTPN2 ZBTB14	29 interacting genes: ATG14 CCDC88A CCDC93 CCHCR1 CCSER2 CDC5L CEP295 COLEC12 DISC1 DST KANSL1 KDM1A LUC7L2 MACF1 MTNR1A NUF2 NUP54 RALA RB1CC1 RESF1 RUBCN SFR1 SH3BP5 SNAPIN SPTAN1 SRGAP2 SYBU TRAF3IP1 TRIO
Entrez ID		81035	55763
HPRD ID		06358	07615
Ensembl ID		ENSG00000158270	ENSG00000090989
Uniprot IDs		Q5KU26	A0A024RDA1 A1LT29 Q9NV70
PDB IDs		2OX8
Enriched GO Terms of Interacting Partners?
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