CDK2AP1 and USP20

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CDK2AP1	USP20
Description		cyclin dependent kinase 2 associated protein 1	ubiquitin specific peptidase 20
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Perinuclear Region Of Cytoplasm	Cytoplasm Centrosome Cytosol Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding DNA Polymerase Binding	G Protein-coupled Receptor Binding Cysteine-type Endopeptidase Activity Thiol-dependent Deubiquitinase Protein Binding Zinc Ion Binding
	Biological Process	Positive Regulation Of Protein Phosphorylation DNA-dependent DNA Replication Cell Cycle	Ubiquitin-dependent Protein Catabolic Process Endocytosis Regulation Of G Protein-coupled Receptor Signaling Pathway Protein Deubiquitination Protein K63-linked Deubiquitination Protein K48-linked Deubiquitination
Pathways			Ub-specific processing proteases
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406) Allergic rhinitis ( 30013184) Allergy ( 27182965) Apolipoprotein A1 levels ( 32203549) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 30072576) Brain morphology (MOSTest) ( 32665545) Heel bone mineral density ( 30598549) Intelligence (MTAG) ( 29326435) Schizophrenia ( 25056061 29483656 23974872) Total cholesterol levels ( 29615537) Tourette syndrome ( 30818990)	Metabolite levels ( 23823483)
Interacting Genes		13 interacting genes: ATPAF2 CARD9 CCDC136 CDK2 CDK2AP2 GRM3 MRFAP1L1 NTAQ1 PICK1 POLA1 SPG21 USP20 ZNF420	69 interacting genes: AGR2 ALAS1 APBA2 ARID5A ASCL1 ATP6V1G2 BEND5 BEND7 BHLHB9 BRPF1 C1QTNF2 CCNL2 CDK2AP1 CLSPN CTAG1A CTAG1B DIO2 ENKD1 EPAS1 FATE1 FTO GPRASP2 GTF2IRD1 HAND2 HIF1A HSF2BP IHO1 IRAK1BP1 ITGB3BP KLHL20 LMNA MAGEA11 MAPK6 MBD3L1 MCCD1 MDFI MEOX2 MRPL28 PBX4 PJA1 PLA2G2A PRKACA PRKCI RAD17 RSPO4 SAMD12 SPRY2 SRGAP2B STING1 TNNI1 TRIB3 TRIM23 TTC19 TTC23L ULK1 USP15 USP21 USP28 VAPA VAPB VAX1 VHL WASHC1 ZBTB10 ZFYVE26 ZNF343 ZNF408 ZNF620 ZXDB
Entrez ID		8099	10868
HPRD ID		03726	07505
Ensembl ID		ENSG00000111328	ENSG00000136878
Uniprot IDs		O14519	Q9Y2K6
PDB IDs		2KW6	6KCZ
Enriched GO Terms of Interacting Partners?
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